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Displaying results 951 - 960 of 10000 in total
  1. Target

    Streptogramin A acetyltransferase

    go.drugbank.com/bio_entities/BE0001238
    TargetEnterococcus faecium

    Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.

    Polypeptides: Streptogramin A acetyltransferase
  2. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001365
    TargetProsthecochloris aestuarii

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  3. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001804
    TargetPaenibacillus polymyxa

    BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.

    Polypeptides: Beta-glucosidase A
  4. Target

    GABA(A) Receptor

    go.drugbank.com/bio_entities/BE0004797
    TargetHumans

    Extrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … Plays an important role in somatosensation and in the production of antinociception (By similarity)

    Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activity
  5. Target

    Apolipoprotein A-IV

    go.drugbank.com/bio_entities/BE0009049
    TargetHumans

    May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. … Apoa-IV is a major component of HDL and chylomicrons

    Polypeptides: Apolipoprotein A-IV
  6. Target

    HSP40, subfamily A

    go.drugbank.com/bio_entities/BE0009270
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: HSP40, subfamily ASynonyms: HSP40, subfamily A, putative
  7. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
  8. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. … While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative

    Synonyms: (7α,17β)-7-{9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl}estra-1(10),2,4-triene-3,17-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Petrolatum

    go.drugbank.com/drugs/DB11058
    ApprovedInvestigational

    A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

    Mixtures: CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant, I-defenseCategories: Compounds used in a research, industrial, or household setting
  10. Indication

    Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089512
    Drugs: Anti-inhibitor coagulant complex · Coagulation factor VIIa Recombinant Human · Emicizumab · Fitusiran · Moroctocog alfa · Rurioctocog alfa pegol +2 more
    Synonyms: Bleeding caused by Hemophilia A