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Ibrutinib
go.drugbank.com/drugs/DB09053ApprovedInvestigationalIt is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. … Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase.
Synonyms: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-oneCategories: Heterocyclic Compounds, 1-RingGuanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release … tablet for the treatment of ADHD.
Categories: MATE 1 Inhibitors, Antihypertensive Agents Indicated for HypertensionProducts: Pro-guanfacine XR, GUAGO 1 MG UZATILMIŞ SALIMLI TABLET, 7 ADETPidolic acid
go.drugbank.com/drugs/DB03088ApprovedInvestigationalPidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics … There are currently little to no medicines available that are clinically approved or marketed for employing pidolic acid as an active ingredient for any particular formal indication.
Mixtures: Cleansing Foaming Gel Acne Pro SkinCategories: Heterocyclic Compounds, 1-RingTenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigationalTenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C). … In October 2023, tenapanor was approved for the treatment of chronic kidney disease.[L48511]
Categories: Drugs for ConstipationProducts: XPHOZAH 10 mg, XPHOZAH 20 mgNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approvedNitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. … [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895]
Categories: Heterocyclic Compounds, 1-Ring, Antibacterials for Systemic UseSynonyms: 1-((5-nitrofurfurylidene)amino)hydantoin, N-(5-Nitrofurfurylidene)-1-aminohydantoinInterferon beta-1a
go.drugbank.com/drugs/DB00060ApprovedInvestigationalHuman interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced.
Categories: interferon beta-1aSynonyms: IFNβ 1a, IFN β-1aTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Synonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: AGGRASTAT CONCENTRATE FOR INFUSION 0.25 mg/ml, AGGRASTAT 0.25mg/ml CONCENTRATE FOR INFUSIONOxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.
Categories: Anesthetics for Topical UseProducts: BENOXINATE % 0.4 GÖZ DAMLASI, 10 ML, Novain 4 mg/ml Augentropfen, LösungIoversol
go.drugbank.com/drugs/DB09134ApprovedInvestigational, which is only indicated for intra-arterial and intravenous use. … Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues.
Categories: Compounds used in a research, industrial, or household settingProducts: Optiray 240 mg J/ml - (nichtionische) parenterale Röntgenkontrastmittellösung, Optiray 300 mg J/ml - (nichtionische) parenterale RöntgenkontrastmittellösungYeast
go.drugbank.com/drugs/DB11017ApprovedYeast allergenic extract is used in allergenic testing.
Products: REFLOR 250 MG KAPSUL, 10 ADET, REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 10 ADET