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Sertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnIt has once again been approved and should soon be available on the French and Australian market. … It is a phenylindole derivative used in the treatment of schizophrenia.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Dopamine D2 Receptor AntagonistsSynonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-onePolyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedPolyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. … PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Categories: Compounds used in a research, industrial, or household settingAcetazolamide
go.drugbank.com/drugs/DB00819ApprovedInvestigationalVet approvedIts antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition … However, its usefulness is transient often because of rapid development of tolerance.
Categories: combinations of sulfonamidesSynonyms: N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide, N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamideTrimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approved[L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of … prevents the synthesis of bacterial DNA and ultimately continued bacterial survival.
Mixtures: Nu-cotrimox-DS Tab 800/160mg, Nu-cotrimox Tab 400/80mgCategories: Metabolic Side Effects of Drugs and SubstancesFluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Categories: Dopamine D2 Receptor AntagonistsInternational brands: Dapotum DMolindone
go.drugbank.com/drugs/DB01618ApprovedAn indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. … Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors.
Categories: Dopamine D2 Receptor AntagonistsIndium In-111 chloride
go.drugbank.com/drugs/DB09490ApprovedIt is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. … Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures
Mixtures: Kit for the Preparation of Indium In 111 Pentetreotide, INDIO (111-IN) OSSINA CURIUM NETHERLANDSSynonyms: Indium chloride In-111, Indium In 111 chlorideLurasidone
go.drugbank.com/drugs/DB08815ApprovedInvestigationalFood and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States. … Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Dopamine D2 Receptor AntagonistsIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigational[L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy. … [L7456,L7459] Irbesartan was granted FDA approval on 30 September 1997.[L7456,L7459]
Mixtures: IRBESARTAN COM PU 300/25, IRBESARTAN COM PU 300/25Categories: Agents Acting on the Renin-Angiotensin SystemHistidine
go.drugbank.com/drugs/DB00117ApprovedInvestigationalNutraceuticalAn essential amino acid that is required for the production of histamine.
Mixtures: SOLUCION DP-AMINE, TRAVASOL PLUS 15% LIBRE DE BISULFITO