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Interleukin-10 receptor subunit beta
go.drugbank.com/bio_entities/BE0014312TargetHumansShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. … The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.
Polypeptides: Interleukin-10 receptor subunit betaSynonyms: IL-10 receptor subunit beta, Cytokine receptor class-II member 4TNF receptor-associated factor 6
go.drugbank.com/bio_entities/BE0021309TargetHumansAdapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (PubMed:12140561, PubMed:19825828, PubMed:8837778).
Polypeptides: TNF receptor-associated factor 6G protein-coupled receptor 6
go.drugbank.com/bio_entities/BE0021832TargetHumansConstitutively active G protein-coupled receptor that maintains high cAMP levels and contributes to several processes including neuronal development, through activation of intracellular signaling pathways
Polypeptides: G protein-coupled receptor 6Synonyms: Sphingosine 1-phosphate receptor GPR6Sodium iodide
go.drugbank.com/drugs/DB11119ApprovedInvestigationalRadiolabelled compound, [DB09293], is used as a diagnostic tool to evaluate thyroid function and morphology. … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine.
Mixtures: Micro+ Te Pediatric, De La Cruz Tincture of IodineProducts: YODURO DE SODIO NA131I SOLUCIÓNINYECTABLEPolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPEG "400" indicates that the average molecular weight of the specific PEG is 400 [L1788]. … It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye [L1785].
Ravagalimab
go.drugbank.com/drugs/DB16676InvestigationalRavagalimab is under investigation in clinical trial NCT03695185 (A Study to Investigate How Well Ravagalimab (ABBV-323) Works and How Safe It Is in Participants With Moderate to Severe Ulcerative Colitis
Prostaglandin E2 receptor EP1 subtype
go.drugbank.com/bio_entities/BE0000064TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system.
Polypeptides: Prostaglandin E2 receptor EP1 subtypeSynonyms: PGE receptor EP1 subtype, Prostanoid EP1 receptorRetinoic acid receptor RXR-beta
go.drugbank.com/bio_entities/BE0000078TargetHumansReceptor for retinoic acid.
Polypeptides: Retinoic acid receptor RXR-betaSynonyms: Retinoid X receptor beta, Nuclear receptor subfamily 2 group B member 2Glutamate receptor ionotropic, kainate 1
go.drugbank.com/bio_entities/BE0000346TargetHumansThe receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist … Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.
Polypeptides: Glutamate receptor ionotropic, kainate 1Synonyms: Glutamate receptor 5, Excitatory amino acid receptor 3Prostaglandin E2 receptor EP2 subtype
go.drugbank.com/bio_entities/BE0000368TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. … The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle
Polypeptides: Prostaglandin E2 receptor EP2 subtypeSynonyms: PGE receptor EP2 subtype, Prostanoid EP2 receptor