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Displaying results 971 - 980 of 10000 in total
  1. Target

    Pepsin A

    go.drugbank.com/bio_entities/BE0004062
    TargetSIV-mac

    Polypeptides: Pepsin A
  2. Target

    Arylsulfatase A

    go.drugbank.com/bio_entities/BE0003195
    TargetEnzymeHumans

    Also involved in the catabolism of other sulfoglycosphingolipids such as SB1a and SM3 (beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) (By similarity) … Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein

    Polypeptides: Arylsulfatase A
  3. Target

    Bontoxilysin-A

    go.drugbank.com/bio_entities/BE0004102
    TargetClostridium botulinum

    Polypeptides: Bontoxilysin-ASynonyms: A, boNT/A
  4. Target

    Filamin-A

    go.drugbank.com/bio_entities/BE0009099
    TargetHumans

    Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. … Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity

    Polypeptides: Filamin-ASynonyms: FLN-A
  5. Target

    Toxin A

    go.drugbank.com/bio_entities/BE0010938
    TargetPeptoclostridium difficile

    Toxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains

    Polypeptides: Toxin A
  6. Drug

    Desmopressin

    go.drugbank.com/drugs/DB00035
    ApprovedInvestigational

    On January 15, 2026, the FDA approved a new low-dose sublingual film formulation specifically for the treatment of nocturia in patients at high risk for fluid overload, utilizing a specialized delivery … It is considered a first-line therapy for central diabetes insipidus but is ineffective in patients with nephrogenic diabetes insipidus, where the kidneys are non-responsive to the hormone [A275458, L56105

    Synonyms: 1 deamino 8 D argininevasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressinProducts: Presinex Nasal Spray 10mcg/dose, MINIRIN NASAL SPRAY 10 mcg/dose
  7. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. … The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621]

    Synonyms: 7(S)-Chloro-7-deoxylincomycin, Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranosideInternational brands: Dalacin C, Dalacin T Topical Solution
  8. Drug

    Fluticasone furoate

    go.drugbank.com/drugs/DB08906
    ApprovedInvestigational

    Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].

    Mixtures: RELVAR® ELLIPTA® 100MCG/25MCG, RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓNCategories: P-glycoprotein inducers, P-glycoprotein substrates
  9. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

    Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocinProducts: Carbetocin Aguettant 100 Mikrogramm/ml Injektionslösung in einer Fertigspritze, PABAL 100 MCG/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 ADET
  10. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

    Mixtures: E-Z-gas II, E-Z-GAS II GRANULESProducts: Sodium Bicarbonate 5% Inj 50mg/ml USP, Sodium Bicarbonate 5% Inj 5gm/100ml USP