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Metformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...
Diethylamino hydroxybenzoyl hexyl benzoate
go.drugbank.com/drugs/DB11269ApprovedDiethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenz...
Mixtures: Wonder Intensive BBCream 21 (Light)Ubrogepant
go.drugbank.com/drugs/DB15328ApprovedInvestigational[erenumab], [fremanezumab], [galcanezumab]) have also been approved in recent years.[A189207] Ubrogepant was approved by Health Canada on November 10, 2022. … [L10926] It was approved by the FDA on December 23, 2019, and is the first oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the acute treatment of migraine.
Categories: Calcitonin Gene-Related Peptide Receptor AntagonistsArdeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnArdeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight of 5500 to 6500.
Elapegademase
go.drugbank.com/drugs/DB14712ApprovedIt can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl
High affinity immunoglobulin epsilon receptor subunit gamma
go.drugbank.com/bio_entities/BE0000049TargetHumansAs a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. … As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit gammaSynonyms: Fc receptor gamma-chain, IgE Fc receptor subunit gammaGamma-aminobutyric acid receptor subunit rho-1
go.drugbank.com/bio_entities/BE0000129TargetHumansRho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (PubMed:37659407). Rho-containing GABA-gated chlorid...
Polypeptides: Gamma-aminobutyric acid receptor subunit rho-1Synonyms: GABA(C) receptor, GABA(A) receptor subunit rho-1Mast/stem cell growth factor receptor Kit
go.drugbank.com/bio_entities/BE0000453TargetHumansKIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. … Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.
Polypeptides: Mast/stem cell growth factor receptor KitGamma-aminobutyric acid receptor subunit alpha-4
go.drugbank.com/bio_entities/BE0000478TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:35355020). GABA-gated chloride channels, also named GABA(A) receptors (...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-4Synonyms: GABA(A) receptor subunit alpha-4Tyrosine-protein phosphatase non-receptor type 1
go.drugbank.com/bio_entities/BE0000623TargetHumansMay also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET
Polypeptides: Tyrosine-protein phosphatase non-receptor type 1