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Displaying results 981 - 990 of 10000 in total
  1. Target

    Synapsin-1

    go.drugbank.com/bio_entities/BE0004488
    TargetHumans

    Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal (PubMed:21441247,...

    Synonyms: Synapsin I
  2. Target

    Copine-1

    go.drugbank.com/bio_entities/BE0009002
    TargetHumans

    Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed:14674885). Involved in the TNF receptor signaling pathway in a calcium-dependent manner (PubMed:14674885). Exhibits calc...

    Synonyms: Copine I
  3. Target

    Actin-1

    go.drugbank.com/bio_entities/BE0009170
    TargetPlasmodium falciparum (isolate HB3)

    Essential for merozoite invasion of, but not adhesion to or reorientation towards, host erythrocytes (By similarity).

    Synonyms: Actin I
  4. Target

    Progonadoliberin-1

    go.drugbank.com/bio_entities/BE0010526
    TargetHumans

    Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones

    Synonyms: Progonadoliberin I
  5. Target

    Tumor susceptibility gene 101 protein

    go.drugbank.com/bio_entities/BE0019070
    TargetHumans

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. … Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation.

    Synonyms: ESCRT-I complex subunit TSG101
  6. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas B
  7. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

    go.drugbank.com/bio_entities/BE0000367
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371, PubMed:32385911, PubMed:33153867). … Complex I functions in the transfer of electrons from NADH to the respiratory chain (PubMed:27626371). The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371)

    Synonyms: Complex I-19kD, Complex I-PGIV
  8. Target

    Insulin-like growth factor 1

    go.drugbank.com/bio_entities/BE0003418
    TargetHumans

    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. … Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to

    Synonyms: IGF-I, Insulin-like growth factor I
  9. Target

    Protease 1

    go.drugbank.com/bio_entities/BE0004345
    TargetAchromobacter lyticus

    Synonyms: Protease I
  10. Drug

    Dimethyl sulfone

    go.drugbank.com/drugs/DB14090
    Investigational

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Nn Bio-MSM 750, Live-well™ OsteMSM 500 Tablet