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Butamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnThe FDA removed all parenteral butamben products from the market, possibly due to the poor solubility of this drug.[A254247,L43942]
Tradipitant
go.drugbank.com/drugs/DB12580ApprovedInvestigational[A275353] Approved by the FDA on December 30, 2025, tradipitant is indicated for the prevention of vomiting induced by motion.
Avapritinib
go.drugbank.com/drugs/DB15233ApprovedInvestigationalAvapritinib was granted FDA approval on 9 January 2020 [L40363] and EMA approval on 24 September 2020.[L41464]
Hydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigational[T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779]
Prednisolone sodium metazoate
go.drugbank.com/drugs/DB05340InvestigationalATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery system that releases the medication only in the colon. Releasing the drug directly into the colon reduces the potential for significant ...
Enfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigationalEnfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers. It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-di...
Tolfenamic acid
go.drugbank.com/drugs/DB09216Approved[L1292] In the US, it presents a Status class I by the FDA. By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of supranuclear palsy.[L1291]
Pectin
go.drugbank.com/drugs/DB11158ApprovedInvestigationalVet approvedUnder the FDA regulation, pectin qualifies as a GRAS (generally recognized as safe) food substance. This status allows pectin to be used with no limitations.[L1960]
Nifedipine
go.drugbank.com/drugs/DB01115ApprovedInvestigational[A190273] Nifedipine was granted FDA approval on 31 December 1981.[L11383]
Bromotheophylline
go.drugbank.com/drugs/DB14018Approved[A33018] Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since March, 1980.