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Birch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational(white birch), although hybrids of both species are used as well. … [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023.
Eucalyptus oil
go.drugbank.com/drugs/DB11114ApprovedEucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit anti...
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome (FCAS)
Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedThe use of P188 as a potential treatment in different pathological conditions, such as chronic microvascular diseases and skeletal muscle deficiencies, is under investigation [A27217]. … P188 was originally approved by the FDA in the 1960s as a therapeutic agent to reduce viscosity in the blood before transfusions, however it is no longer available in any approved products [A27217].
Procaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedProcaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic.
Maralixibat
go.drugbank.com/drugs/DB16226ApprovedInvestigational[A239249] Surgical interventions such as partial external bile diversion and ileal exclusion have also been used as treatments. … Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like [odevixibat].
Omega-3-acid ethyl esters
go.drugbank.com/drugs/DB09539ApprovedInvestigationalOmega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza[FDA Label][L5849].
Trabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalOn October 23, 2015, the FDA approved trabectedin, (as Yondelis), for the treatment of specific soft tissue sarcomas. … Food and Drug Administration (FDA) have approved trabectedin as an orphan drug in soft tissue sarcomas and ovarian cancer.
Cinnamyl alcohol
go.drugbank.com/drugs/DB14186ApprovedDue to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as [DB14184] within commercial products.
Succinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures.