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Hydrocortisone succinate
go.drugbank.com/drugs/DB14545ApprovedInvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersProducts: SOLU-CORTEF FOR INJECTION 100 mg/vial, SOLU-CORTEF® 100 MG POLVO PARA INYECCIONTolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnIt is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone, 3,4-dihydroxy-5-nitro-4'-methylbenzophenoneIsavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalAs isavuconazole displays low water solubility, it is found as an active ingredient of its prodrug, [DB06636]. … Resistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label].
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesProducts: CRESEMBA (100 MG HARD CAPSULES), CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL)Castor oil
go.drugbank.com/drugs/DB11113ApprovedNutraceuticalVet approvedCastor oil is a rich source of [DB02955], which represents up to 90% of the total castor oil content. … It can also be found in hard candies as a release agent and anti-sticking agent, or supplementary vitamins and mineral oral tablets as an ingredient for protective coatings.
Products: RICIPAN 64 GR 150 ML EMULSIYON, RICIMENT 120 ML EMULSIYONTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approved[A1279,A1281,L9068] Terbinafine hydrochloride was granted FDA approval on 30 December 1992.[L9064]
Mixtures: M-FURO MANT % 0.1 + % 1 KREM, 20GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPrednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approved[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Mixtures: BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersLithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalLithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label]. … Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843].
Products: LITHURIL 300 MG KAPSUL, 100 ADET, LİTOMAKS 300 MG SERT KAPSÜL, 100 ADETAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigational[L4799] Other biosimilars include adalimumab-fkjp - which was approved in July 2022 -,[L42495] adalimumab-bwwd - which was approved in August 2022 -,[L42935], adalimumab-aacf - which was approved in October … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA.[A39983] This drug is frequently known as _Humira_.
Products: HUMIRA 40 MG, HUMIRA 40 MG/0.4 MLXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … It is widely used as a sugar substitute and in "sugar-free" food products.
Products: Xylifresh 100 (peppermint) - Gum 827 mg, Xylifresh 100 (spearmint) - GumFlavoxate
go.drugbank.com/drugs/DB01148ApprovedIt may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem] … A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear.
Products: สะปาสดิก - 100, FLOVOX® 200 MG