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Stavudine
go.drugbank.com/drugs/DB00649ApprovedInvestigationalA dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Synonyms: 2',3'-Didehydro-3'-deoxythimidine, 1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymineMixtures: TRESLAM ® 30, COVIRO ® LSSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigationalSumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.
Synonyms: 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide, (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamideMixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTAChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnMedications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.
Synonyms: 1-(p-chlorobenzenesulfonyl)-3-propylurea, 1-(p-chlorophenylsulfonyl)-3-propylureaCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnThioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). … A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity.
Synonyms: 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazineInternational brands: Mellaril-SMoricizine
go.drugbank.com/drugs/DB00680ApprovedWithdrawnAn antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Synonyms: ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate, [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl esterCategories: Antiarrhythmics, Class I, Heterocyclic Compounds, 1-RingDaunorubicin
go.drugbank.com/drugs/DB00694ApprovedInvestigationalA very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Synonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione, Leukaemomycin CCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexAmprenavir
go.drugbank.com/drugs/DB00701ApprovedWithdrawnAmprenavir is a protease inhibitor used to treat HIV infection.
Synonyms: (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamateCategories: P-glycoprotein inducers, P-glycoprotein substratesClodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approvedClodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.
Atracurium besylate
go.drugbank.com/drugs/DB00732ApprovedA non-depolarizing neuromuscular blocking agent with short duration of action.
Categories: Heterocyclic Compounds, 2-RingProducts: ./5 มล. ชนิดฉีด), DEMATRAC 50 MG/5 ML İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPULPentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other t...
Synonyms: p,p'-(pentamethylenedioxy)dibenzamidine, 1,5-bis(4-amidinophenoxy)pentaneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates