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Displaying results 1 - 10 of 524 in total
  1. Target

    Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

    go.drugbank.com/bio_entities/BE0000423
    TargetTransporterHumans

    Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. … Transports non-alpha-amino acids such as beta-alanine with low affinity, and has a higher affinity for dipolar and cationic amino acids such as leucine and lysine (PubMed:18599538).

    Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)Synonyms: Amino acid transporter ATB0+
  2. Target

    Acid ceramidase

    go.drugbank.com/bio_entities/BE0010906
    TargetHumans

    Lysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH (PubMed:10610716, PubMed:11451951, PubMed:15655246, PubMed:26898341, PubMed:36752535, PubMed … Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine (PubMed:12764132, PubMed:12815059).

    Polypeptides: Acid ceramidaseSynonyms: Acid CDase
  3. Target

    Iduronic acid

    go.drugbank.com/bio_entities/BE0004822
    TargetHumans

  4. Target

    Uric acid

    go.drugbank.com/bio_entities/BE0004823
    TargetHumans

  5. Target

    Hyaluronic acid

    go.drugbank.com/bio_entities/BE0009857
    TargetHumans and other mammals

  6. Target

    Fatty acid

    go.drugbank.com/bio_entities/BE0009632
    Target

  7. Target

    Bile acid-CoA:amino acid N-acyltransferase

    go.drugbank.com/bio_entities/BE0002303
    TargetEnzymeHumans

    In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (PubMed:12810727) … Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PubMed:12239217, PubMed:12810727, PubMed:2037576, PubMed:8034703).

    Polypeptides: Bile acid-CoA:amino acid N-acyltransferaseSynonyms: Bile acid-CoA thioesterase
  8. Target

    Fatty acid synthase

    go.drugbank.com/bio_entities/BE0000959
    TargetEnzymeHumans

    Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. … This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain

    Polypeptides: Fatty acid synthaseSynonyms: Type I fatty acid synthase
  9. Target

    Fatty-acid peroxygenase

    go.drugbank.com/bio_entities/BE0001960
    TargetEnzymeBacillus subtilis (strain 168)

    Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.

    Polypeptides: Fatty-acid peroxygenaseSynonyms: Fatty acid beta-hydroxylase
  10. Target

    Lysosomal acid glucosylceramidase

    go.drugbank.com/bio_entities/BE0000978
    TargetEnzymeHumans

    same chain length of saturated fatty acids (such as beta-D-glucosyl-N-octadecanoyl-sphing-4-enine) (PubMed:24211208). … Plays a central role in the degradation of complex lipids and the turnover of cellular membranes (PubMed:27378698).

    Polypeptides: Lysosomal acid glucosylceramidaseSynonyms: Acid beta-glucosidase, Lysosomal acid GCase