Search

Displaying all 4 results
DrugBest match

Belumosudil

go.drugbank.com/drugs/DB16703
ApprovedInvestigational

Belumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension. It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC50...

  1. Pathway

    Belumosudil Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174776
    Metabolic

    Metabolites of Belumosudil are predicted with biotransformer.

    Drugs: Mesoheme · Belumosudil
  2. Drug

    Axatilimab

    go.drugbank.com/drugs/DB16388
    ApprovedInvestigational

    [A264309] Approved treatment options in steroid-refractory cGHVD are limited, and include [ruxolitinib], [ibrutinib], and [belumosudil].

  3. Indication

    Chronic Graft-Versus-Host Disease

    go.drugbank.com/conditions/DBCOND0045787
    Drugs: Axatilimab · Belumosudil · Ibrutinib · Ruxolitinib · TRGFT-201 · Thalidomide