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Cytochrome P450 2C19
go.drugbank.com/bio_entities/BE0003536EnzymeTargetHumansHydroxylates fenbendazole at the 4' position (PubMed:23959307)
Synonyms: Fenbendazole monooxygenase (4'-hydroxylating)Cytochrome P450 3A4
go.drugbank.com/bio_entities/BE0002638TargetEnzymeHumansCatalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole (PubMed:10759686). Hydroxylates antimalarial drug quinine (PubMed:8968357).
Cytochrome P450 3A Subfamily
go.drugbank.com/bio_entities/BE0004866EnzymeTargetHumansCatalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole (PubMed:10759686). Hydroxylates antimalarial drug quinine (PubMed:8968357).
Cytochrome P450 2J2
go.drugbank.com/bio_entities/BE0003683EnzymeHumansCatalyzes hydroxylation of the anthelmintics albendazole and fenbendazole (PubMed:23959307). Catalyzes the sulfoxidation of fenbedazole (PubMed:19923256)