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DrugBest match

Fenbendazole

go.drugbank.com/drugs/DB11410
InvestigationalVet approved

Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is a...

  1. Drug

    Oxfendazole

    go.drugbank.com/drugs/DB11446
    InvestigationalVet approved

    Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

    Synonyms: Fenbendazole S-oxide, Fenbendazole sulfoxide
  2. Target

    Cytochrome P450 2C19

    go.drugbank.com/bio_entities/BE0003536
    EnzymeTargetHumans

    Hydroxylates fenbendazole at the 4' position (PubMed:23959307)

    Synonyms: Fenbendazole monooxygenase (4'-hydroxylating)
  3. Target

    Cytochrome P450 3A4

    go.drugbank.com/bio_entities/BE0002638
    TargetEnzymeHumans

    Catalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole (PubMed:10759686). Hydroxylates antimalarial drug quinine (PubMed:8968357).

  4. Target

    Cytochrome P450 3A Subfamily

    go.drugbank.com/bio_entities/BE0004866
    EnzymeTargetHumans

    Catalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole (PubMed:10759686). Hydroxylates antimalarial drug quinine (PubMed:8968357).

  5. Target

    Cytochrome P450 2J2

    go.drugbank.com/bio_entities/BE0003683
    EnzymeHumans

    Catalyzes hydroxylation of the anthelmintics albendazole and fenbendazole (PubMed:23959307). Catalyzes the sulfoxidation of fenbedazole (PubMed:19923256)