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Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone
smpdb.ca/view/SMP0000333SignalingIn the ovary, the FSH receptor is necessary for follicular development and is expressed on the granulosa cells. In the male the FSH receptor has been identified on the Sertoli cells that are critical for spermatogenesis. The FSH receptor...
Enzymes: Follitropin subunit betaEtonogestrel Action Pathway
smpdb.ca/view/SMP0126525Drug actionEtonogestrel is a synthetic metabolite of progestin desosgestrel. This drug is a long-acting progestin contraceptive used mostly in intradermal implants that are releasing 40 mcg/day of the drug for 3 years. Etonogestrel binds strongly t...
Enzymes: Follitropin subunit betaProgesterone Action Pathway
smpdb.ca/view/SMP0126529Drug actionProgesterone is a hormone naturally occurring in females. This molecule is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. It is used as an oral drug as a contraceptive to preven...
Enzymes: Follitropin subunit betaNorethisterone Action Pathway
smpdb.ca/view/SMP0126536Drug actionNorethisterone, also known as norethindrone, is a synthetic progestational hormone used for contraception, prevention of endometrial hyperplasia (hormone replacement therapy), and in the treatment of other hormone-related illnesses. This...
Enzymes: Follitropin subunit betaSegesterone acetate Action Pathway
smpdb.ca/view/SMP0126542Drug actionSegesterone acetate, also known as Annovera, is a synthetic progestin derived from 19-norprogesterone. This drug is very potent; it mediates progestational activity 100 times higher than that of progesterone. It is used as a contraceptiv...
Enzymes: Follitropin subunit betaMegestrol acetate Action Pathway
smpdb.ca/view/SMP0126528Drug actionMegestrol acetate is a synthetic progestational hormone initially developed as a contraceptive. Nowadays, it is used as a drug to treat anorexia and cachexia (or unexplained weight loss) and as an antineoplastic agent to treat inoperable...
Enzymes: Follitropin subunit betaNorelgestromin Action Pathway
smpdb.ca/view/SMP0126539Drug actionNorelgestromin is a synthetic progestational hormone indicated in women to prevent pregnancy. This drug is also used in menopausal hormonal therapy. This drug is administered as a contraceptive pill or as a transdermal patch. This drug i...
Enzymes: Follitropin subunit betaNorgestrel Action Pathway
smpdb.ca/view/SMP0126522Drug actionNorgestrel is a synthetic progestin that has 2 stereoisomers, the active one is called levonorgestrel and the other one is dextronorgestrel. This drug is used in combination with ethinyl estradiol for oral contraception and prevention of...
Enzymes: Follitropin subunit betaDrospirenone Action Pathway
smpdb.ca/view/SMP0126538Drug actionDrospirenone is a synthetic progestin commonly found in popular oral contraceptives like Yaz, Angeliq, and Loryna. This drug is also indicated to control acne, menopause-associated symptoms, and premenstrual dysphoric disorder (PMDD) whe...
Enzymes: Follitropin subunit betaDienogest Action Pathway
smpdb.ca/view/SMP0126541Drug actionDienogest is a semisynthetic progestogen derived from 19-nortestosterone and has antiandrogenic properties. This drug is used as a contraceptive or to treat endometriosis alone or combined with ethinylestradiol. Dienogest acts by binding...
Enzymes: Follitropin subunit beta