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Infliximab
go.drugbank.com/drugs/DB00065
ApprovedInvestigational
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammat...
Certolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigationalCertolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacin...
Moderately to Severely Active Crohn's Disease
go.drugbank.com/conditions/DBCOND0093405Moderately to Severely Active Ulcerative Colitis
go.drugbank.com/conditions/DBCOND0105407Moderately to Severely Active Rheumatoid Arthritis
go.drugbank.com/conditions/DBCOND0109811Psoriatic Arthritis
go.drugbank.com/conditions/DBCOND0028320Drugs: Abatacept · Adalimumab · Betamethasone · Bupivacaine · Certolizumab pegol · Corticotropin +14 moreAnkylosing Spondyloarthritis
go.drugbank.com/conditions/DBCOND0057824