Chronic Plaque Psoriasis (DBCOND0033442)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Infliximab	A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis.	Tumor necrosis factortarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03598790	A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis	Bimekizumab	treatment	3	completed
NCT01200264	Apremilast for Chronic Plaque Psoriasis (CPP) Patients Who Have Failed One Course of Biologic Therapy	Apremilast	treatment	2	withdrawn
NCT00972543	Raptiva in Palm and Sole Psoriasis	Efalizumab	treatment	4	terminated
NCT00512187	Moderate Weight Loss Makes Obese Patients With Severe Chronic Plaque Psoriasis Responsive to Sub-Optimal Dose of Cyclosporine: an Investigator Blinded, Controlled, Randomized Clinical Trial	No drug interventions	treatment	4	completed
NCT03370133	A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis	Bimekizumab Ustekinumab	treatment	3	completed
NCT00799877	Chronic Plaque Psoriasis (Ps) Registry	No drug interventions	Not Available	Not Available	completed
NCT03412747	A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis	Adalimumab Bimekizumab	treatment	3	completed
NCT00794807	Safety and Tolerability of Repeat Courses of IM Alefacept	Alefacept	treatment	4	completed
NCT03025542	A Study to Evaluate the Pharmacokinetics (PK), Pharmacodynamics (PD), and Safety of Bimekizumab in Patients With Chronic Plaque Psoriasis	Bimekizumab	treatment	2	completed
NCT04221906	Study to Evaluate the Safety and Antipsoriatic Efficacy of BOS-475 in a Psoriasis Plaque Test	Betamethasone Calcipotriol	treatment	1	completed
NCT02969018	Study To Evaluate Safety And Efficacy Of PF-06700841 In Subjects With Moderate To Severe Plaque Psoriasis	PF-06700841	treatment	2	completed
NCT00422617	Evaluate the Efficacy and Safety of One Course of Amevive in Taiwan Patients	Alefacept	educational_counseling_training	Not Available	completed
NCT00472758	A Multicenter Study to Evaluate the Safety and Tolerability of Single-Dose for MEDI-545	Sifalimumab	treatment	1	completed
NCT00844363	Narrowband UVB Phototherapy in the Treatment of Psoriasis Vulgaris	No drug interventions	treatment	Not Available	terminated
NCT04211363	Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis	Roflumilast	treatment	3	completed
NCT00419666	A Study of Calcitriol BID Topical Treatment in Adolescents With Plaque Psoriasis	Calcitriol	treatment	2	completed
NCT00245765	Efficacy Study of CDP870 in Subjects With Chronic Plaque Psoriasis Who Are Candidate for Systemic Therapy and/or Phototherapy/Photochemotherapy	Certolizumab pegol	treatment	2	completed
NCT00770965	Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis	Secukinumab	treatment	2	completed
NCT00739882	TRUST Study: Raptiva ® in Hand & Foot Psoriasis	Efalizumab	treatment	4	terminated
NCT00233662	Safety and Tolerability of Repeat Courses of IM Alefacept	Alefacept	treatment	3	completed
NCT00539929	Paired-Comparison Study Evaluating the Efficacy and Safety of E6201 Versus Vehicle for the Treatment of Plaque-Type Psoriasis	E-6201	treatment	2	completed
NCT04211389	Twin Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis	No drug interventions	treatment	3	completed
NCT03230292	A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Adult Patients With Chronic Plaque Psoriasis	Bimekizumab	treatment	2	completed
NCT03410992	A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis	Bimekizumab	treatment	3	completed
NCT03536884	A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis	Bimekizumab Secukinumab	treatment	3	completed
NCT06011733	A Study to Evaluate the Efficacy and Safety of Bimekizumab in Chinese Adult Study Participants With Moderate to Severe Plaque Psoriasis	Bimekizumab	treatment	3	active_not_recruiting
NCT00795353	Assess the Long-term Effectiveness and Safety of Amevive (Alefacept) in Subjects With Moderate to Severe Chronic Plaque Psoriasis	Alefacept	Not Available	Not Available	terminated
NCT02581345	Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis	Adalimumab	treatment	3	completed
NCT00697593	ChangE From Any Systemic psoriasiS therapY to Raptiva	Efalizumab	treatment	4	terminated
NCT01358578	Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects With Moderate to Severe, Chronic Plaque-Type Psoriasis	Etanercept Secukinumab	treatment	3	completed
NCT04286607	Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis	Roflumilast	treatment	3	completed
NCT00673556	A Study to Assess the Efficacy and Safety of Alefacept in Psoriasis Patients for Whom Conventional Treatment is Ineffective or Inappropriate	Alefacept	treatment	3	completed
NCT03766685	A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Moderate to Severe Chronic Plaque Psoriasis (PSO)	Bimekizumab	treatment	3	completed
NCT00705900	LCD Solution Versus Calcipotriol Cream in the Treatment of Moderate Plaque Psoriasis	Calcipotriol	treatment	Not Available	completed
NCT03897075	Efficacy and Safety Study of Tildrakizumab in the Treatment of Nail Psoriasis	Tildrakizumab	treatment	3	active_not_recruiting
NCT00707070	Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis	Acitretin Efalizumab	treatment	4	unknown_status
NCT02905006	Study to Evaluate Safety and Efficacy of Different Doses of Bimekizumab in Patients With Chronic Plaque Psoriasis	Bimekizumab	treatment	2	completed
NCT00574249	Adalimumab in Combination With Topical Treatment (Calcipotriol/Betamethasone) in Subjects With Moderate to Severe Psoriasis and Insufficient Response to Classic Systemic Treatment	Adalimumab Betamethasone Calcipotriol	treatment	3	completed
NCT00493324	Study to Evaluate the Immune Response to Pneumococcal Vaccine in Alefacept-treated Adults With Chronic Plaque Psoriasis	Alefacept Streptococcus pneumoniae type 1 capsular polysaccharide antigen Streptococcus pneumoniae type 10a capsular polysaccharide antigen Streptococcus pneumoniae type 11a capsular polysaccharide antigen Streptococcus pneumoniae type 12f capsular polysaccharide antigen Streptococcus pneumoniae type 14 capsular polysaccharide antigen Streptococcus pneumoniae type 15b capsular polysaccharide antigen Streptococcus pneumoniae type 17f capsular polysaccharide antigen Streptococcus pneumoniae type 18c capsular polysaccharide antigen Streptococcus pneumoniae type 19a capsular polysaccharide antigen Streptococcus pneumoniae type 19f capsular polysaccharide antigen Streptococcus pneumoniae type 2 capsular polysaccharide antigen Streptococcus pneumoniae type 20 capsular polysaccharide antigen Streptococcus pneumoniae type 22f capsular polysaccharide antigen Streptococcus pneumoniae type 23f capsular polysaccharide antigen Streptococcus pneumoniae type 3 capsular polysaccharide antigen Streptococcus pneumoniae type 33f capsular polysaccharide antigen Streptococcus pneumoniae type 4 capsular polysaccharide antigen Streptococcus pneumoniae type 5 capsular polysaccharide antigen Streptococcus pneumoniae type 6b capsular polysaccharide antigen Streptococcus pneumoniae type 7f capsular polysaccharide antigen Streptococcus pneumoniae type 8 capsular polysaccharide antigen Streptococcus pneumoniae type 9n capsular polysaccharide antigen Streptococcus pneumoniae type 9v capsular polysaccharide antigen	prevention	4	completed
NCT00350116	Topical Vitamin B12 in Chronic Plaque Psoriasis	Cyanocobalamin	treatment	3	completed
NCT00674063	A Study to Assess the Efficacy and Safety of Two Dosing Regimens of Alefacept in Subjects Weighing Between 100kg and 150kg With Moderate to Severe Chronic Plaque Psoriasis	Alefacept	treatment	3	completed
NCT03010527	A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Patients With Chronic Plaque Psoriasis	Bimekizumab	treatment	2	completed
NCT00438360	Efficacy and Safety of Cyclosporine A Microemulsion in Maintenance Patients With Chronic Plaque Psoriasis	Cyclosporine	treatment	3	completed
NCT03982394	Observational Study of Patients With Moderate to Severe Chronic Plaque Psoriasis	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT00805480	Multiple-loading Dose Regimen Study in Patients With Chronic Plaque-type Psoriasis	Secukinumab	treatment	2	completed
NCT00953329	Alefacept in Subjects With Chronic Plaque Psoriasis Who Failed to Respond to Anti-TNF Therapy	Alefacept	treatment	4	terminated
NCT02852967	A Phase 2, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Belumosudil in Subjects With Moderate/Severe Chronic Plaque Psoriasis	Belumosudil L-Acetylleucine	treatment	2	completed
NCT02690701	Study to Evaluate the Effect of Secukinumab Compared to Placebo on Aortic Vascular Inflammation in Subjects With Moderate to Severe Plaque Psoriasis	Secukinumab	treatment	4	completed
NCT01872546	Skin Transcriptional Profiles In Psoriatic Patients Under Adalimumab Biotherapy	Adalimumab	Not Available	2	completed
NCT02570750	The Effect Of Smoking Status Of The Patient On The Success Of Etanercept Therapy In Psoriasis	No drug interventions	Not Available	Not Available	completed