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Alprazolam Action Pathway
smpdb.ca/view/SMP0125056Drug actionAlprazolam may also be prescribed off-label for insomnia, premenstrual syndrome, and depression. . … Alprazolam is also indicated, either as a standard or extended-release formulation, for the treatment of panic disorder with or without agoraphobia in adults.
Alprazolam Predicted Metabolism Pathway
smpdb.ca/view/SMP0174641MetabolicMetabolites of sildenafil are predicted with biotransformer.
Metabolism and Physiological Effects of Orotic acid
smpdb.ca/view/SMP0124870MetabolicOrotic acid (orotate) is classified as a pyrimidinemonocarboxylic acid. Most urinary orotic acid is synthesized in the body, where it arises as an intermediate in the pathway for the synthesis of pyrimidine nucleotides. It originates fro...
Enzymes: Neutral amino acid transporter B(0)Metabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicUridine, also known as beta-uridine or 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione, is a member of the class of compounds known as pyrimidine nucleosides. Pyrimidine nucleosides are compounds comprising a pyrimidine base attached t...
Enzymes: Neutral amino acid transporter B(0)Metabolism and Physiological Effects of 2-Aminobenzoic acid
smpdb.ca/view/SMP0126869Disease2-Aminobenzoic acid, also known as anthranilic acid or O-aminobenzoate, belongs to the class of organic compounds known as aminobenzoic acids. These are benzoic acids containing an amine group attached to the benzene moiety. Within human...
Enzymes: B(0,+)-type amino acid transporter 1Argininemia
smpdb.ca/view/SMP0000357DiseaseArgininemia is caused by a mutation in the gene ARG, encoding liver arginase, which hydrolyses arginine to urea and ornithine in the last step of the urea cycle. A defect in liver arginase causes accumulation of ammonia in blood; arginin...
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Neutral amino acid transporter B(0)Citrullinemia Type I
smpdb.ca/view/SMP0000001DiseaseCitrullinemia Type 1, also called argininosuccinate synthetase deficiency, argininosuccinic acid synthetase deficiency or ASS deficiency, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of the urea cycle cause...
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Neutral amino acid transporter B(0)Urea Cycle
smpdb.ca/view/SMP0000059MetabolicUrea, also known as carbamide, is a waste product made by a large variety of living organisms and is the main component of urine. Urea is created in the liver, through a string of reactions that are called the Urea Cycle. This cycle is a...
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Neutral amino acid transporter B(0)Carbamoyl Phosphate Synthetase Deficiency
smpdb.ca/view/SMP0000002DiseaseCCarbamoyl Phosphate Synthetase Deficiency, also called hyperammonemia due to carbamoyl phosphate synthetase 1 deficiency, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of the urea cycle caused by a defectiv...
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Neutral amino acid transporter B(0)Argininosuccinic Aciduria
smpdb.ca/view/SMP0000003DiseaseArgininosuccinic Aciduria, (Argininosuccinase Deficiency, Argininosuccinate Lyase Deficiency, ASL Deficiency) is an autosomal recessive disorder caused by a mutation in the ASL gene which codes for argininosuccinate lyase. It results in ...
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Neutral amino acid transporter B(0)