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Displaying all 7 results
  1. Target

    Voltage-gated Potassium Channels

    go.drugbank.com/bio_entities/BE0009847
    Target

    During conditions of increased substrate load, maintains the driving force for proximal tubular and intestinal sodium ions absorption, gastric acid secretion, and cAMP-induced jejunal chloride ions secretion … When associated with KCNE3, forms the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions (PubMed:10646604).

    Polypeptides: A-type voltage-gated potassium channel KCND1, A-type voltage-gated potassium channel KCND2Synonyms: Shal-type potassium channel KCND1, Minimal potassium channel
  2. Target

    Potassium channel subfamily T member 1

    go.drugbank.com/bio_entities/BE0015369
    TargetHumans

    Contributes to synaptic development and plasticity (By similarity) … Sodium-activated K(+) channel (PubMed:37494189). Acts as an important mediator of neuronal membrane excitability (PubMed:37494189). Contributes to the delayed outward currents (By similarity).

    Polypeptides: Potassium channel subfamily T member 1Synonyms: Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2
  3. Target

    Potassium channel subfamily T member 2

    go.drugbank.com/bio_entities/BE0015626
    TargetHumans

    Sodium-activated and chloride-activated potassium channel (PubMed:14684870, PubMed:16687497, PubMed:25214519, PubMed:27682982, PubMed:29069600, PubMed:29740868).

    Polypeptides: Potassium channel subfamily T member 2Synonyms: Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1, Sequence like an intermediate conductance potassium channel subunit
  4. Target

    Potassium voltage-gated channel subfamily KQT member 1

    go.drugbank.com/bio_entities/BE0000672
    TargetHumans

    During conditions of increased substrate load, maintains the driving force for proximal tubular and intestinal sodium ions absorption, gastric acid secretion, and cAMP-induced jejunal chloride ions secretion … When associated with KCNE3, forms the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions (PubMed:10646604).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 1Synonyms: Voltage-gated potassium channel subunit Kv7.1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
  5. Target

    Solute carrier family 12 member 1

    go.drugbank.com/bio_entities/BE0000502
    TargetTransporterHumans

    Renal sodium, potassium and chloride non-electrogenic ion symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration … and volume regulation (PubMed:21321328).

    Synonyms: Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
  6. Target

    Solute carrier family 12 member 2

    go.drugbank.com/bio_entities/BE0000281
    TargetTransporterHumans

    Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:16669787, PubMed:32081947, PubMed:32294086, PubMed:33597714 … Plays a vital role in the regulation of ionic balance and cell volume (PubMed:16669787, PubMed:32081947, PubMed:32294086, PubMed:7629105)

    Synonyms: Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
  7. Target

    P2 Purinoceptors

    go.drugbank.com/bio_entities/BE0009827
    Target

    ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:9016352). … ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:12761352).