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Displaying results 1 - 10 of 51 in total
  1. Target

    Chloroquine resistance transporter

    go.drugbank.com/bio_entities/BE0009205
    TargetTransporterPlasmodium falciparum

    Required for the asexual intraerythrocytic proliferation of parasites (PubMed:35867395).

    Polypeptides: Chloroquine resistance transporter
  2. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutase
  3. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed:18316031). … Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A (PubMed:18316031, PubMed:22665496).

    Polypeptides: Receptor for retinol uptake STRA6
  4. Target

    Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

    go.drugbank.com/bio_entities/BE0001300
    TargetHumans

    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

    Polypeptides: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
  5. Target

    Multidrug resistance protein 1

    go.drugbank.com/bio_entities/BE0009167
    TargetTransporterPlasmodium falciparum (isolate FC27 / Papua New Guinea)

    Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

    Synonyms: Chloroquine resistance protein
  6. Target

    Advanced glycation end product-specific receptor

    go.drugbank.com/bio_entities/BE0010032
    TransporterTargetHumans

    Protects cells from DNA replication stress by localizing to damaged replication forks where it stabilizes the MCM2-7 complex and promotes faithful progression of the replication fork (PubMed:36807739).

    Synonyms: Receptor for advanced glycation end products, Receptor for advanced glycosylation end products
  7. Target

    Calcium-dependent secretion activator 2

    go.drugbank.com/bio_entities/BE0008710
    TargetHumans

    Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release fr...

    Synonyms: Calcium-dependent activator protein for secretion 2
  8. Target

    Hyaluronan mediated motility receptor

    go.drugbank.com/bio_entities/BE0004702
    TargetHumans

    Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs.

    Synonyms: Receptor for hyaluronan-mediated motility
  9. Target

    Calcium-dependent secretion activator 1

    go.drugbank.com/bio_entities/BE0008704
    TargetHumans

    Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading o...

    Synonyms: Calcium-dependent activator protein for secretion 1
  10. Target

    L-allo-threonine aldolase

    go.drugbank.com/bio_entities/BE0002839
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: L-allo-threonine aldolaseFunction: L-allo-threonine aldolase activity