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Bifunctional PGK/TIM
go.drugbank.com/bio_entities/BE0001611TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Polypeptides: Bifunctional PGK/TIMSynonyms: TIMImmunoglobulin heavy constant gamma 2
go.drugbank.com/bio_entities/BE0003805TargetHumansConstant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...
Synonyms: Ig gamma-2 chain C region TILTyrosine-protein kinase receptor Tie-1
go.drugbank.com/bio_entities/BE0009396TargetHumansTransmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis
Polypeptides: Tyrosine-protein kinase receptor Tie-1Synonyms: TIETIR domain-containing adapter molecule 1
go.drugbank.com/bio_entities/BE0016552TargetHumansLigand binding to these receptors results in TRIF recruitment through its TIR domain (PubMed:12471095, PubMed:12539043, PubMed:14739303).
Polypeptides: TIR domain-containing adapter molecule 1Synonyms: Proline-rich, vinculin and TIR domain-containing protein B, TIR domain-containing adapter protein inducing IFN-betaImmunoglobulin heavy variable 3-23
go.drugbank.com/bio_entities/BE0004165TargetHumansV region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Synonyms: Ig heavy chain V-III region TILIgG heavy chain
go.drugbank.com/bio_entities/BE0010027TargetCarrierConstant region of immunoglobulin (Ig) heavy chains. Igs are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors, which upon binding ...
Synonyms: Ig gamma-2 chain C region TILTriosephosphate isomerase, glycosomal
go.drugbank.com/bio_entities/BE0001603TargetTrypanosoma cruziSynonyms: TIMTriosephosphate isomerase
go.drugbank.com/bio_entities/BE0001256TargetPlasmodium falciparumCatalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic and gluconeogenic pathways.
Synonyms: TIMTriosephosphate isomerase
go.drugbank.com/bio_entities/BE0001877TargetGeobacillus stearothermophilusInvolved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Synonyms: TIMToll-like receptor 2
go.drugbank.com/bio_entities/BE0001164TargetHumansCooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (...
Synonyms: TIL4