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Lymphocyte antigen 75
go.drugbank.com/bio_entities/BE0010744TargetHumansActs as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes
Polypeptides: Lymphocyte antigen 75Synonyms: Ly-75Matrix metalloproteinase-25
go.drugbank.com/bio_entities/BE0009742TargetHumansMay activate progelatinase A
Polypeptides: Matrix metalloproteinase-25Synonyms: MMP-25NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000493TargetHumansCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:3155...
Polypeptides: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialHeat shock protein 75 kDa, mitochondrial
go.drugbank.com/bio_entities/BE0014134TargetHumansChaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the bala...
Polypeptides: Heat shock protein 75 kDa, mitochondrialSynonyms: HSP 75Synaptosomal-associated protein 25
go.drugbank.com/bio_entities/BE0000390TargetHumanst-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulat...
Polypeptides: Synaptosomal-associated protein 25Synonyms: SNAP-25, Synaptosomal-associated 25 kDa proteinVitamin D 25-hydroxylase
go.drugbank.com/bio_entities/BE0000524EnzymeHumansCatalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol) (PubMed:12867411, PubMed:15465040, PubMed:18511070). … Can metabolize vitamin D analogs/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives (PubMed:15465040, PubMed:18511070).
Polypeptides: Vitamin D 25-hydroxylaseSolute carrier family 25 member 32
go.drugbank.com/bio_entities/BE0000730TransporterHumansFacilitates flavin adenine dinucleotide (FAD) translocation across the mitochondrial inner membrane into the mitochondrial matrix where it acts as a redox cofactor to assist flavoenzyme activities in fundamental metabolic processes inclu...
Polypeptides: Solute carrier family 25 member 3225-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
go.drugbank.com/bio_entities/BE0000443EnzymeTargetHumansConverts 24R,25-dihydroxyvitamin D3/secalciferol to 1-alpha,24,25-trihydroxyvitamin D3, an active ligand of VDR. Also active on 25-hydroxyvitamin D2 (PubMed:10518789). … D3, 1alpha,25-dihydroxyvitamin D3/calcitriol that acts via the vitamin D receptor (VDR) (PubMed:10518789, PubMed:10566658, PubMed:12050193, PubMed:22862690, PubMed:9486994).
Polypeptides: 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialSynonyms: 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylaseAdenosylmethionine-8-amino-7-oxononanoate aminotransferase
go.drugbank.com/bio_entities/BE0001519TargetEscherichia coli (strain K12)Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA) (PubMed:1092681, PubMed:1092682). It is the only animotransferase known ...
Synonyms: DANSMitochondrial ornithine transporter 1
go.drugbank.com/bio_entities/BE0000201TargetHumansMitochondrial ornithine-citrulline antiporter (Probable) (PubMed:12807890, PubMed:22262851). Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of orni...
Synonyms: Solute carrier family 25 member 15