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Displaying results 1 - 10 of 92 in total
  1. Target

    Apolipoprotein B-100

    go.drugbank.com/bio_entities/BE0009908
    TargetHumans

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor

    Polypeptides: Apolipoprotein B-100Synonyms: Apo B-100
  2. Target

    mRNA of ApoB-100

    go.drugbank.com/bio_entities/BE0004845
    TargetHumans

  3. Target

    Matrix metalloproteinase-24

    go.drugbank.com/bio_entities/BE0003699
    TargetHumans

    Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by...

    Polypeptides: Matrix metalloproteinase-24Synonyms: MMP-24
  4. Target

    Cholesterol 24-hydroxylase

    go.drugbank.com/bio_entities/BE0010886
    TargetEnzymeHumans

    Primarily catalyzes the hydroxylation (with S stereochemistry) at C-24 of cholesterol side chain, triggering cholesterol diffusion out of neurons and its further degradation (PubMed:10377398, PubMed:14640697

    Polypeptides: Cholesterol 24-hydroxylaseSynonyms: Cholesterol 24-monooxygenase
  5. Target

    Delta(24)-sterol reductase

    go.drugbank.com/bio_entities/BE0014791
    TargetHumans

    Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:22178193, PubMed:25637936).

    Polypeptides: Delta(24)-sterol reductaseSynonyms: 24-dehydrocholesterol reductase, 3-beta-hydroxysterol Delta-24-reductase
  6. Target

    Serine/threonine-protein kinase 24

    go.drugbank.com/bio_entities/BE0009383
    TargetHumans

    Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JN...

    Polypeptides: Serine/threonine-protein kinase 24
  7. Target

    C-C motif chemokine 24

    go.drugbank.com/bio_entities/BE0011045
    TargetHumans

    Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line (PubMed:9104803, PubMed:9365122). Binds to CCR3 (PubMed:9104803, PubMed:9365122)

    Polypeptides: C-C motif chemokine 24
  8. Target

    1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

    go.drugbank.com/bio_entities/BE0002250
    TargetEnzymeHumans

    With initial hydroxylation at C-24 (via C24-oxidation pathway), performs a sequential 6-step oxidation of calcitriol leading to the formation of the biliary metabolite calcitroic acid (PubMed:15574355,

    Polypeptides: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialSynonyms: 24-OHase, Vitamin D(3) 24-hydroxylase
  9. Target

    Homeobox protein engrailed-2

    go.drugbank.com/bio_entities/BE0004484
    TargetHumans

    Synonyms: Hu-En-2, Homeobox protein en-2
  10. Target

    Transitional endoplasmic reticulum ATPase

    go.drugbank.com/bio_entities/BE0004572
    TargetHumans

    The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic

    Synonyms: 15S Mg(2+)-ATPase p97 subunit