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Empagliflozin
Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies, for the management of type 2 diabetes mellitus. The...
Linagliptin
go.drugbank.com/drugs/DB08882ApprovedInvestigationalLinagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated b...
Mixtures: Glyxambi Film-Coated Tablets 25mg/5mg (Empagliflozin 25mg/ Linagliptin 5mg), Glyxambi Film-Coated Tablets 10mg/5mg (Empagliflozin 10mg / Linagliptin 5mg)Categories: linagliptin and empagliflozin, metformin, linagliptin and empagliflozinChronic Kidney Disease (CKD)
go.drugbank.com/conditions/DBCOND0048800Symptomatic Congestive Heart Failure
go.drugbank.com/conditions/DBCOND0055215Metformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...
Categories: metformin and empagliflozin, metformin, linagliptin and empagliflozinEnd Stage Renal Disease (ESRD)
go.drugbank.com/conditions/DBCOND0035540Avenciguat
go.drugbank.com/drugs/DB18882InvestigationalAvenciguat is under investigation in clinical trial NCT05282121 (A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis
Vicadrostat
go.drugbank.com/drugs/DB21693InvestigationalVicadrostat is under investigation in clinical trial NCT07064473 (A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular
Cardiovascular Mortality
go.drugbank.com/conditions/DBCOND0040959Drugs: Acetylsalicylic acid · Canagliflozin · Colchicine · Dapagliflozin · Empagliflozin · Evolocumab +12 moreType 2 Diabetes
go.drugbank.com/conditions/DBCOND0030616