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Padimate O
go.drugbank.com/drugs/DB11570ApprovedPadimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA [L2153]. … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic effects on yeast i_n vivo_ [A32458].
Synonyms: Padimate O, Padimate-OMixtures: Sun and Ski Stick SPF 15, Aruba Aloe Lip Sunscreen and MoisturizerPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Synonyms: Petrolatum, Petrolatum baseMixtures: PETROLATUM and LANOLIN, PETROLATUM and LANOLINPadimate A
go.drugbank.com/drugs/DB11229ApprovedWithdrawnPadimate A is an ester derivative of PABA and an ingredient in some sunscreens. … It absorbs ultraviolet rays thereby preventing sunburn, however, its chemical structure and behaviour is similar to an industrial free radical generator.
Synonyms: Padimate A, PadimateMineral oil
go.drugbank.com/drugs/DB11057ApprovedInvestigationalVet approvedMineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and prevent dry, rough, scaly, itchy skin and minor skin irritations. … Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that are then further refined.
Mixtures: Mineral Oil, Petrolatum and Phenylephrine HCl, Hand and Skin ShieldCategories: Alimentary Tract and Metabolism, Basic Ointments and ProtectantsSmallpox and Monkeypox Vaccine, Live, Non-replicating
go.drugbank.com/drugs/DB15497ApprovedSynonyms: Smallpox and Monkeypox Vaccine, Live, Non-replicatingAllogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
go.drugbank.com/drugs/DB16709ApprovedSheets containing this scaffold product are applied to the burn site and, as they contain metabolically active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular … [L35505] It was developed as an alternative to autografting - the process by which a patient's own skin is harvested and grafted onto the burn site - which has the disadvantage of creating a new wound
Synonyms: Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized layered scaffold, Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagenMetocurine
go.drugbank.com/drugs/DB01336ApprovedPatients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393] … Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant.
Categories: Heterocyclic Compounds, 2-RingSynonyms: O,O-DimethylchondrocurarineVayarin
go.drugbank.com/drugs/DB09328ApprovedCost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure [L1502]. … A slow response time of 12 weeks is an impediment to successful management of ADHD as only 41.6% of subjects prescribed Vayarin remained compliant for the duration of the study.
Synonyms: Phosphatidylserine, DHA, and EPACategories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesSynonyms: o-Chloroxazepam, o-ChlorooxazepamMalathion
go.drugbank.com/drugs/DB00772ApprovedMalathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Categories: Scabicides, Insecticides and Repellents, Antiparasitic Products, Insecticides and RepellentsSynonyms: O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl), O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl