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Displaying results 1 - 10 of 4412 in total
  1. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    [A179761] Sumatriptan was granted FDA approval on 28 December 1992.[L6805] … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.

    Synonyms: Sumatriptan, SumatriptánSalts: Sumatriptan succinate, Sumatriptan hemisulfate
  2. Drug

    Eucommia ulmoides bark

    go.drugbank.com/drugs/DB14259
    Investigational

    Eucommia ulmoides bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Du Zhong, Du-Zhong
  3. Drug

    Duvakitug

    go.drugbank.com/drugs/DB19444
    Investigational

    Duvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).

    Synonyms: Du vakitug, Immunoglobulin G1 [de-449-lysine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal TEV-48574 γ1-chain), disulfide with human monoclonal TEV-48574 λ-chain, dimer
  4. Pathway

    Sumatriptan Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126984
    Drug action

    Sumatriptan inhibits the presynaptic terminal of the trigeminal nucleus caudalis, which leads to the reversal of facial allodynia. … Sumatriptan is a 5-HT1B/1D receptor agonist and leads to vasoconstriction in the basilar artery and the blood vessels of the dura mater.

    Drugs: ATP · Sumatriptan · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
  5. Drug

    Acheta domesticus

    go.drugbank.com/drugs/DB10866
    Approved

    House cricket allergenic extract is used in allergenic testing.

    Synonyms: Acheta domesticus
  6. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that ar...

    Mixtures: Dg Health Hemorrhoidal, DG Health HemorrhoidalProducts: Siero Du Kind Cleansing Sherbet, OLIO DI VASELINA
  7. Drug

    Poloxamer 188

    go.drugbank.com/drugs/DB11333
    ApprovedInvestigational

    Due to its sufactant properties, P188 may also be found in over-the-counter (OTC) products such as toothpaste, laxatives and mouthwash, and used in various cosmetic, industrial and pharmaceutical applications

    Products: Kang Du Qing, Mayer /Kang Du Qing
  8. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    Due to its renewability and high versatility in addition to being the only commercial source of a hydroxylated fatty acid [A31170], castor oil has been used as a vital raw material for the chemical industry

    Products: OLIO DI RICINO, Huile De Ricin
  9. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethor...

    Mixtures: De-Chlor DM, Syrup DM-DCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist
  10. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and used as an expectorant . Since that ...

    Mixtures: Syrup DM-D-E, Benylin DM-D-EProducts: DG Health Mucus ER, SelectHealth Tussin DM