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Displaying results 1 - 10 of 399 in total
  1. Drug

    Valaciclovir

    go.drugbank.com/drugs/DB00577
    ApprovedInvestigational

    Valaciclovir (valacyclovir), also known as _Valtrex_, is an antiviral drug that has been used to manage and treat various herpes infections for more than 2 decades. … One major use of valacyclovir is the treatment of genital herpes episodes or outbreaks.

    Synonyms: Valacyclovir, ValaciclovirSalts: Valaciclovir hydrochloride, Valaciclovir hydrochloride monohydrate
  2. Pathway

    Valacyclovir Action Pathway

    smpdb.ca/view/SMP0125888
    Drug action

    Valacyclovir is rapidly and almost completely converted in man to aciclovir and valine, likely by the enzyme valacyclovir hydrolase. … Valaciclovir (valacyclovir), also known as the brand name Valtrex, is an guanine nucleoside antiviral used to treat herpes exacerbations. Valaciclovir is the L-valine ester of aciclovir.

    Drugs: Valine · Valaciclovir · Acyclovir · Magnesium cation
    Enzymes: Valacyclovir hydrolase
  3. Drug

    Candicidin

    go.drugbank.com/drugs/DB01152
    ApprovedInvestigationalWithdrawn

    Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.

    Synonyms: Levorin, Levorina
  4. Drug

    Human varicella-zoster immune globulin

    go.drugbank.com/drugs/DB11621
    ApprovedInvestigational

    Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). … The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus.

    Categories: Human Varicella Zoster Immune GlobulinsSynonyms: Varicella zoster immune globulin, Varicella-zoster immune globulin
  5. Drug

    Varicella zoster vaccine (recombinant)

    go.drugbank.com/drugs/DB13924
    ApprovedInvestigational

    Herpes zoster, also known as shingles, is caused by a reactivation of Varicella Zoster Virus (VZV), the virus that commonly causes Chickenpox in childhood. … The main immunological component of Shingrix vaccine is glycoprotein E (gE), a protein found on the surface of varicella zoster virus (VZV).

    Categories: Varicella Zoster VaccinesSynonyms: gE recombinant Varicella zoster virus (VZV) glycoprotein E, Recombinant Varicella zoster virus (VZV) glycoprotein E
  6. Drug

    Varicella zoster vaccine (live/attenuated)

    go.drugbank.com/drugs/DB10318
    ApprovedInvestigational

    Varicella Zoster Virus (VZV) is the virus that commonly causes Chickenpox (also known as Varicella) in childhood [L1040]. … Both Varivax and Zostavax are composed of a lyophilized preparation of live, attenuated Oka/Merck strain of varicella-zoster virus.

    Categories: Varicella Zoster Vaccines, Live Attenuated Herpes Zoster Virus VaccineSynonyms: Zoster Vaccine, Live, varicella-zoster live virus
  7. Drug

    Anakinra

    go.drugbank.com/drugs/DB00026
    ApprovedInvestigational

    This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. … Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues.

    Categories: Interleukin-1 Receptor AntagonistSynonyms: Interleukin-1 receptor antagonist anakinra
  8. Drug

    Varicella zoster virus envelope glycoprotein e

    go.drugbank.com/drugs/DB33826
    Investigational

    Synonyms: Herpes zoster vaccine gsk1437173a, Varicella zoster virus envelope glycoprotein e
  9. Drug

    Satralizumab

    go.drugbank.com/drugs/DB15762
    ApprovedInvestigational

    until it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to act again. … uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors occurs in a pH-dependent manner[A218551] - this allows satralizumab to bind an IL-6 receptor

    Categories: Interleukin-6 Receptor AntagonistSynonyms: Humanised anti-IL-6 receptor monoclonal antibody
  10. Drug

    Nipocalimab

    go.drugbank.com/drugs/DB16257
    ApprovedInvestigational

    Nipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases.

    Synonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonal, Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimerCategories: Neonatal Fc Receptor Blocker