Displaying drugs 976 - 1000 of 15549 in total
Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6b individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Description: … It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes ... 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. ... Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a …
Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 1 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... capsular antigens of *Streptococcus pneumoniae* serotype 1 individually conjugated to the CRM197 protein, a …
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 5 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated ... Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... capsular antigens of *Streptococcus pneumoniae* serotype 5 individually conjugated to the CRM197 protein, a …
Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle
Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ …
Reslizumab
Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Matched Description: … Elevated levels of eosinophils increase the risk for asthma exacerbations, including both allergic forms ... IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment ... It is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving …
Matched Categories: … Drugs for Obstructive Airway Diseases …
Matched Categories: … Drugs for Obstructive Airway Diseases …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Iupac: … 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... acts as a cardiac stimulant without beta adrenergic activity. …
Matched Mixtures name: … NEBIVOLOLO E IDROCLOROTIAZIDE MYLAN PHARMA ... NEBIVOLOLO E IDROCLOROTIAZIDE MYLAN PHARMA ... NEBIVOLOLO E IDROCLOROTIAZIDE EG …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … NEBIVOLOLO E IDROCLOROTIAZIDE ACCORD …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... acts as a cardiac stimulant without beta adrenergic activity. …
Matched Mixtures name: … NEBIVOLOLO E IDROCLOROTIAZIDE MYLAN PHARMA ... NEBIVOLOLO E IDROCLOROTIAZIDE MYLAN PHARMA ... NEBIVOLOLO E IDROCLOROTIAZIDE EG …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antihypertensive Agents Indicated for Hypertension …
Matched Products: … NEBIVOLOLO E IDROCLOROTIAZIDE ACCORD …
Argatroban
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary intervention. Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients...
Approved
Investigational
Matched Iupac: … (2R,4R)-1-[(2S)-5-carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4- ... methylpiperidine-2-carboxylic acid …
Matched Description: … Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT ... have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary ... Argatroban is a direct, selective thrombin inhibitor. …
Matched Salts cas: … 141396-28-3 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Description: … Argatroban is a non-heparin anticoagulant shown to both normalize platelet count in patients with HIT ... have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary ... Argatroban is a direct, selective thrombin inhibitor. …
Matched Salts cas: … 141396-28-3 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Oxetacaine
Oxetacaine, also called oxethazaince, is a potent surface analgesic with the molecular formula N, N-bis-(N-methyl-N-phenyl-t-butyl-acetamide)-beta-hydroxyethylamine that conserves its unionized form at low pH levels. Its actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer. Oxetacaine is approved by Health Canada since 1995 for...
Approved
Investigational
Matched Iupac: … 2-[(2-hydroxyethyl)({[methyl(2-methyl-1-phenylpropan-2-yl)carbamoyl]methyl})amino]-N-methyl-N-(2-methyl ... -1-phenylpropan-2-yl)acetamide …
Matched Description: … [A33104] Oxetacaine is approved by Health Canada since 1995 for its use as an antacid combination in ... Oxetacaine, also called oxethazaince, is a potent surface analgesic with the molecular formula N, N-bis ... N-methyl-N-phenyl-t-butyl-acetamide)-beta-hydroxyethylamine that conserves its unionized form at low pH levels …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Description: … [A33104] Oxetacaine is approved by Health Canada since 1995 for its use as an antacid combination in ... Oxetacaine, also called oxethazaince, is a potent surface analgesic with the molecular formula N, N-bis ... N-methyl-N-phenyl-t-butyl-acetamide)-beta-hydroxyethylamine that conserves its unionized form at low pH levels …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Plantago lanceolata pollen
Plantago lanceolata pollen is the pollen of the Plantago lanceolata plant. Plantago lanceolata pollen is mainly used in allergenic testing.
Approved
Matched Description: … Plantago lanceolata pollen is mainly used in allergenic testing. …
Oprelvekin
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Description: … in Escherichia coli (E. coli) by recombinant DNA technology. ... With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids ... in length in comparison to the natural IL-11, which is 178 amino acid long. …
Gestrinone
Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatment of endometriosis.
Gestrinone was developed in the early 1970s and was tested clinically as...
Approved
Matched Iupac: … (1R,3aS,3bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Gestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive ... Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group ... in Europe and North America. …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Description: … Gestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive ... Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group ... in Europe and North America. …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Sarecycline
Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Iupac: … 3,10,12,12a-tetrahydroxy-7-{[methoxy(methyl)amino]methyl}-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … low propensity for resistance development in such pathogens and a narrower, more specific spectrum of ... for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients ... exist for treating acne vulgaris, sarecycline presents a new and innovative therapy choice because it …
Matched Salts cas: … 1035979-44-2 …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Anti-Acne Preparations for Systemic Use …
Matched Description: … low propensity for resistance development in such pathogens and a narrower, more specific spectrum of ... for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients ... exist for treating acne vulgaris, sarecycline presents a new and innovative therapy choice because it …
Matched Salts cas: … 1035979-44-2 …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Anti-Acne Preparations for Systemic Use …
Cilgavimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for ... [A243356, A243361] Cilgavimab (formerly AZD1061) is a recombinant monoclonal antibody produced in Chinese ... hamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a natural …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Tixagevimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Matched Description: … December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for ... [A243356, A243361] Tixagevimab (formerly AZD8895) is a recombinant monoclonal antibody produced in Chinese ... hamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a natural …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Experimental Unapproved Treatments for COVID-19 …
Turmeric oil
Approved
Experimental
Chromium nicotinate
Approved
Experimental
Matched Iupac: … chromium(3+) tris(pyridine-3-carboxylate) …
Matched Mixtures name: … Ribotin-E ... Zintrexyl-C ... Omega-3 Rx Complete …
Matched Mixtures name: … Ribotin-E ... Zintrexyl-C ... Omega-3 Rx Complete …
LetibotulinumtoxinA
The aesthetic utility of botulinum toxin was discovered incidentally following its initial use in the treatment of facial spasmodic disorders in the early 1970s. The first aesthetic use of botulinum toxin was reported in 1989, when onabotulinumtoxinA (Botox) was used as a treatment for facial asymmetry resulting from iatrogenic facial...
Approved
Matched Synonyms: … BoNT/A-DS …
Matched Description: … [L42330] LetibotulinumtoxinA has been a market-leading cosmetic product in South Korea for a number of ... [L42335] It was approved for use in the treatment of glabellar lines in Canada in June 2022[L42330,L42335 ... [A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since …
Matched Categories: … Botulinum Toxins, Type A …
Matched Description: … [L42330] LetibotulinumtoxinA has been a market-leading cosmetic product in South Korea for a number of ... [L42335] It was approved for use in the treatment of glabellar lines in Canada in June 2022[L42330,L42335 ... [A249920] It was subsequently approved by the FDA in 1992 for use in aesthetic procedures and has since …
Matched Categories: … Botulinum Toxins, Type A …
Iva annua pollen
Iva annua pollen is the pollen of the Iva annua plant. Iva annua pollen is mainly used in allergenic testing.
Approved
Matched Description: … Iva annua pollen is mainly used in allergenic testing. …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Description: … Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Givosiran
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic disorder in which ... [L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States ... Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical …
Relugolix
Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids, and more recently by the United States' FDA in 2020, under the brand name...
Approved
Investigational
Matched Iupac: … 1-(4-{1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxo- ... 1H,2H,3H,4H-thieno[2,3-d]pyrimidin-6-yl}phenyl)-3-methoxyurea …
Matched Description: … of testosterone levels when compared to [leuprolide], another androgen deprivation therapy used in the ... Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several ... It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment …
Matched Description: … of testosterone levels when compared to [leuprolide], another androgen deprivation therapy used in the ... Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several ... It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment …
Haloprogin
Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes (Trichophyton, Microsporum and Epidermophyton). Commonly these infections are named for the body part affected, including tinea corporis (general skin),...
Approved
Withdrawn
Matched Iupac: … 1,2,4-trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene …
Matched Description: … Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. ... Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. ... Haloprogin is no longer available in the United States and has been discontinued. …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Matched Description: … Haloprogin is used as a topical ointment or cream in the treatment of Tinea infections. ... Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. ... Haloprogin is no longer available in the United States and has been discontinued. …
Matched Categories: … Antifungals for Topical Use ... Antifungals for Dermatological Use …
Upadacitinib
Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Iupac: … (3S,4R)-3-ethyl-4-{1,5,7,10-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),3,7,9,11-pentaen-12-yl}-N-(2,2,2 …
Matched Description: … [A189165] The FDA approved upadacitinib in August 2019 and it is used for the treatment of active ... [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients ... drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. …
Matched Description: … [A189165] The FDA approved upadacitinib in August 2019 and it is used for the treatment of active ... [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients ... drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. …
Callistemon citrinus pollen
Callistemon citrinus pollen is the pollen of the Callistemon citrinus plant. Callistemon citrinus pollen is mainly used in allergenic testing.
Approved
Matched Description: … Callistemon citrinus pollen is mainly used in allergenic testing. …
Thonzylamine
Thonzylamine is an antihistamine and anticholinergic drug. It is available as combination products with DB04837 or DB00388 for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Approved
Matched Iupac: … N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine …
Matched Description: … It is available as combination products with [DB04837] or [DB00388] for temporary relief of symptoms …
Matched Categories: … Antihistamines for Topical Use ... Antihistamines for Systemic Use …
Matched Description: … It is available as combination products with [DB04837] or [DB00388] for temporary relief of symptoms …
Matched Categories: … Antihistamines for Topical Use ... Antihistamines for Systemic Use …
Displaying drugs 976 - 1000 of 15549 in total