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Displaying drugs 1051 - 1075 of 11817 in total
Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … Nimodipine is a 1,4-dihydropyridine calcium channel blocker. …
Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 2. The vaccine contains purified and inactivated poliovirus type 2 that were...
Approved
Investigational
Matched Description: … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization ... The vaccine contains purified and inactivated poliovirus type 2 that were grown from a continuous line …
Acer rubrum pollen is the pollen of the Acer rubrum plant. Acer rubrum pollen is mainly used in allergenic testing.
Approved
American chestnut allergenic extract is used in allergenic testing.
Approved
Diaminopyrimidine oxide is a compound similar to minoxidil which is used to aid in hair growth.
Approved
Matched Description: … Diaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth. …
Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Approved
Illicit
Matched Description: … Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause ... Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent …
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical …
Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. It is known to bind and block the activity of plasma cholinesterases.
Approved
Matched Description: … Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate …
Approved
Experimental
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Description: … persistant severe nerve pain that develops as a result of chronic pain from shingles lesions. ... Herpes zoster, also known as shingles, is caused by a reactivation of Varicella Zoster Virus (VZV), the ... Following initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within …
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Acer saccharum pollen is the pollen of the Acer saccharum plant. Acer saccharum pollen is mainly used in allergenic testing.
Approved
White mustard seed allergenic extract is used in allergenic testing.
Approved
Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis for percutaneous use. It is administered to prevent the development of tuberculosis.
Approved
Matched Description: … Bacillus calmette-guerin substrain tice live antigen is a vaccine containing attenuated live culture …
Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as sunitinib and imatinib. Ripretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020....
Approved
Matched Description: … treatment with a minimum of 3 other kinase inhibitors. ... Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST ... [L13769] It is the first drug approved as a fourth-line therapy in the specific setting of prior …
Solenopsis richteri allergenic extract is used in allergenic testing. It is extracted from the black imported fire ant which is native to South Amercia. The species has also been introduced in North Amercia. When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with...
Approved
Melilotus albus pollen is the pollen of the Melilotus albus plant. Melilotus albus pollen is mainly used in allergenic testing.
Approved
Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, Carica papaya and Vasconcellea cundinamarcensis. The enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a crude latex. Papain...
Approved
Matched Description: … catalytic diad that plays a role in breaking peptide bonds. ... Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found ... enzyme is found to be localized in the skin of papaya, and is collected from slashed unripe papayas as a
A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Description: … A second-line antitubercular agent that inhibits mycolic acid synthesis. …
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Description: … rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to ... ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from ... Currently, only thrombin derived from bovine blood is available in the U.S. as a stand-alone thrombin …
Rumex acetosella pollen is the pollen of the Rumex acetosella plant. Rumex acetosella pollen is mainly used in allergenic testing.
Approved
Rumex altissimus pollen is the pollen of the Rumex altissimus plant. Rumex altissimus pollen is mainly used in allergenic testing.
Approved
Displaying drugs 1051 - 1075 of 11817 in total