Displaying drugs 10776 - 10800 of 11755 in total
Deutivacaftor
Deutivacaftor is under investigation in clinical trial NCT03227471 (A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis).
Investigational
Matched Description: … Deutivacaftor is under investigation in clinical trial NCT03227471 (A Study of VX-445 in Healthy Subjects …
MK-0736
MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).
Investigational
Matched Description: … MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial …
Sepiapterin
Sepiapterin is under investigation in clinical trial NCT03519711 (A Study of CNSA-001 in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia).
Investigational
Matched Description: … Sepiapterin is under investigation in clinical trial NCT03519711 (A Study of CNSA-001 in Primary Tetrahydrobiopterin …
Mibavademab
Mibavademab is under investigation in clinical trial NCT04159415 (Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy).
Investigational
Matched Description: … Mibavademab is under investigation in clinical trial NCT04159415 (Study of REGN4461, a Leptin Receptor …
BS-001
BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Description: … BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell …
Petosemtamab
Petosemtamab is under investigation in clinical trial NCT03526835 (A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors).
Investigational
Matched Description: … Petosemtamab is under investigation in clinical trial NCT03526835 (A Study of Bispecific Antibody MCLA …
Pegtarviliase
Pegtarviliase is under investigation in clinical trial NCT05154890 (A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency).
Investigational
Matched Description: … Pegtarviliase is under investigation in clinical trial NCT05154890 (A Multiple Ascending Dose Study of …
Mivelsiran
Mivelsiran is under investigation in clinical trial NCT06393712 (A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy).
Investigational
Matched Description: … Mivelsiran is under investigation in clinical trial NCT06393712 (A Phase 2 Trial of ALN-APP in Patients …
TTP889
TTP889, an orally bioavailable selective inhibitor of the intrinsic coagulation pathway, is being developed as an anticoagulant for the treatment of thromboembolic disorders. TTP889 is the only known selective small molecule inhibitor of Factor IX, a key enzyme of the intrinsic pathway of the blood coagulation system. TTP889 has proven...
Investigational
Matched Description: … TTP889 is the only known selective small molecule inhibitor of Factor IX, a key enzyme of the intrinsic …
Fiboflapon
Investigational
Omapatrilat
Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling. This drug from BMS was not approved by the FDA due...
Investigational
KW-7158
KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels...
Investigational
Matched Description: … KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary ... The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) …
GEM-231
GEM231 is a second-generation antisense oligonucleotide targeting the mRNA of the R1alpha regulatory subunit of cAMP dependent protein kinase. A monoclonal antibody combined with a toxic substance that is used treat certain types of acute myeloid leukemia in older patients and is being studied in the treatment of other types...
Investigational
Matched Description: … A monoclonal antibody combined with a toxic substance that is used treat certain types of acute myeloid ... GEM231 is a second-generation antisense oligonucleotide targeting the mRNA of the R1alpha regulatory …
FAV-201
FAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma.
Investigational
Matched Description: … FAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma. …
Lexatumumab
Lexatumumab is a fully humanized, high-affinity immunoglobulin G(1 lambda) monoclonal antibody (mAb).
Investigational
Matched Description: … Lexatumumab is a fully humanized, high-affinity immunoglobulin G(1 lambda) monoclonal antibody (mAb). …
Perifosine
Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition.
Investigational
Matched Description: … Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase …
Teclozan
Teclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections.
Experimental
Matched Description: … Teclozan is an antiprotozoal agent employed typically as a therapy to treat protozoan infections. …
SCH-58500
SCH-58500 is a recombinant replication-deficient adenovirus vector carrying the human p53 gene.
Investigational
Matched Description: … SCH-58500 is a recombinant replication-deficient adenovirus vector carrying the human p53 gene. …
MDX-1097
MDX-1097 is a chimeric monoclonal antibody directed against the kappa myeloma antigen (KMA).
Investigational
Matched Description: … MDX-1097 is a chimeric monoclonal antibody directed against the kappa myeloma antigen (KMA). …
PT886
PT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47)
Investigational
Matched Description: … PT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47) …
Emodepside
Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively new class of anthelmintic.
Investigational
Vet approved
Matched Description: … Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, ... is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively …
Isaralgagene civaparvovec
Isaralgagene civaparvovec, formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A (α-Gal A) enzyme. It is developed by Sangamo Therapeutics and investigated in Fabry Disease.
Investigational
Matched Description: … (α-Gal A) enzyme. ... formerly known as ST-920, is liver-tropic rAAV 2/6 vector carrying the cDNA for human alpha-galactosidase A …
SGX-523
A MET receptor tyrosine kinase inhibitor.
Investigational
Matched Description: … A MET receptor tyrosine kinase inhibitor. …
Pipazethate
A non-narcotic oral antitussive agent.
Experimental
Matched Description: … A non-narcotic oral antitussive agent. …
Trimazosin
Trimazosin is a sympatholytic alpha blocker.
Experimental
Matched Description: … Trimazosin is a sympatholytic alpha blocker. …
Displaying drugs 10776 - 10800 of 11755 in total