Displaying drugs 11076 - 11100 of 12129 in total
PD-169316
PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Description: … PD-169316 is a p38 MAP kinase inhibitor.[A253062] …
PD-173952
PD-173952 is a potent Myt1 kinase inhibitor.
Investigational
Matched Description: … PD-173952 is a potent Myt1 kinase inhibitor.[A253067] …
Tabituximab barzuxetan yttrium Y-90
A version of tabituximab barzuxetan radiolabeled with yttrium-90.
Investigational
Matched Description: … A version of [tabituximab barzuxetan] radiolabeled with yttrium-90. …
Boron
Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard...
Experimental
Matched Description: … It is a low-abundant metalloid that is a poor electrical conductor at room temperature. ... Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in ... There are few pharmaceutical agents that contain a boron molecule in their structures, such as [DB09041 …
Ligelizumab
Ligelizumab is a humanized IgG1k monoclonal antibody targeted against immunoglobulin E (IgE). Similar in mechanism to omalizumab, another IgE-directed monoclonal antibody, ligelizumab has a distinct binding epitope as compared to its peer (with a small degree of overlap) which appears to confer a greater affinity for free serum IgE and...
Investigational
Matched Description: … binding epitope as compared to its peer (with a small degree of overlap) which appears to confer a greater ... Ligelizumab is a humanized IgG1k monoclonal antibody targeted against immunoglobulin E (IgE). ... Similar in mechanism to [omalizumab], another IgE-directed monoclonal antibody, ligelizumab has a distinct …
Dihydromorphine
A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Experimental
Illicit
Matched Description: … A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem] …
EHC18
EHC18 is an immune regulation medicine. It is a broad spectrum of specific HCV proteins.
Investigational
Matched Description: … It is a broad spectrum of specific HCV proteins. …
XR5944
XR5944 is a DNA bis-intercalating anticancer drug. It has both intercalating and antineoplastic activities.
Investigational
Matched Description: … XR5944 is a DNA bis-intercalating anticancer drug. …
FLX475
FLX475 is a small molecule CCR4 antagonist being investigated for the treatment of cancer.
Investigational
Matched Description: … FLX475 is a small molecule CCR4 antagonist being investigated for the treatment of cancer.[L9875] …
BI-765063
BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα).
Investigational
Matched Description: … BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα). …
NXC680
NXC680 is a small molecule under investigation for the treatment of idiopathic pulmonary fibrosis (IPF).
Investigational
Matched Description: … NXC680 is a small molecule under investigation for the treatment of idiopathic pulmonary fibrosis (IPF …
S-Hydroxycysteine
S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. It targets the proteins subtilisin BPN', glutathione S-transferase A1,...
Experimental
Matched Description: … S-hydroxycysteine is a solid. This compound belongs to the alpha amino acids and derivatives. ... group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a …
Velusetrag
Velusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research...
Investigational
Matched Description: … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. ... Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research …
Sumanirole
Investigational
RUS 3108
RUS 3108 is being developed for the treatment of atherosclerosis, the major cause of cardiovascular disorders such as heart attacks and stroke by Dr. Reddy’s Laboratories.
The drug’s Phase I clinical trials have been initiated in Europe to assess safety of the drug compound in healthy volunteers.
Investigational
Ularitide
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is ... Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated …
TAFA-93
TAFA93 is a novel prodrug of the mTOR inhibitor rapamycin which has successfully completed Phase 1 clinical development. mTOR inhibitors are currently used in the prevention of organ rejection in transplantation, the treatment of autoimmune and oncological diseases, and as a component of coated stents for the treatment of coronary...
Investigational
Matched Description: … TAFA93 is a novel prodrug of the mTOR inhibitor rapamycin which has successfully completed Phase 1 clinical ... of organ rejection in transplantation, the treatment of autoimmune and oncological diseases, and as a …
SYNB1891
SYNB1891 is a live, modified strain of the probiotic Escherichia coli Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway. SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult...
Investigational
Matched Description: … cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway. ... SYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce …
Rupintrivir
Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV) infections. Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells. It is designed to combat colds caused by rhinovirus.
Investigational
Matched Description: … Rupintrivir is a rhinovirus 3C protease inhibitor in development for use against human rhinoviral (HRV ... Rupintrivir was active against all 48 HRV serotypes tested in a cell protection assay in H1-HeLa cells …
INGN 225
INGN 225 is a therapeutic consisting of a cancer patient's own immune cells treated with an adenovector carrying the human p53 gene, Ad-p53. INGN 225 is currently in Phase 1/2 trials in patients with small cell lung cancer and breast cancer.
Investigational
Matched Description: … INGN 225 is a therapeutic consisting of a cancer patient's own immune cells treated with an adenovector …
(4R)-limonene
Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Description: … flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery. ... citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a …
Rosemary
Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. …
Ipafricept
Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).
Investigational
Matched Description: … Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 …
Hemoporfin
Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Investigational
Matched Description: … Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children …
Orelabrutinib
Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)).
Investigational
Matched Description: … Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With …
Displaying drugs 11076 - 11100 of 12129 in total