Displaying drugs 11176 - 11200 of 11797 in total
Remternetug
Remternetug is under investigation in clinical trial NCT05463731 (A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)).
Investigational
Matched Description: … Remternetug is under investigation in clinical trial NCT05463731 (A Study of Remternetug (LY3372993) …
Palifosfamide
Palifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.
Investigational
Matched Description: … Palifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. …
siG12D LODER
siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).
Investigational
Matched Description: … siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in …
ICG-136
ICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics. It was investigated for the treatment of acute myeloid leukemia.
Investigational
Matched Description: … ICG-136 is a compound chimeric antigen receptor (cCAR) T-cell therapy developed by iCell Gene Therapeutics …
IMMU-114
IMMU-114 is antibody-drug conjugate consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a CL2A linker.
Investigational
Matched Description: … consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a …
Nalorphine
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Experimental
Vet approved
Matched Description: … Nalorphine is a mixed opioid agonist–antagonist. ... It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid …
Gam-COVID-Vac
Gam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia. The vaccine candidate is a heterologous COVID-19 vaccine containing two components, recombinant adenovirus type 26 (rAd26) vector and recombinant adenovirus type 5 (rAd5) vector which both carry the SARS-CoV-2 spike glycoprotein. The vaccine is offered in both...
Investigational
Matched Description: … The vaccine candidate is a heterologous COVID-19 vaccine containing two components, recombinant adenovirus ... The vaccine is offered in both a frozen (Gam-COVID-Vac) and freeze-dried formulation (lyophilizate; Gam-COVID-Vac ... Preliminary results suggested that all participants developed antibodies to the SARS-CoV-2 glycoproteins with a …
XAV-19
XAV-19 is an intravenous antibody-based treatment targeted towards SARS-CoV-2 and other coronaviruses[L16553,L16558]. The therapy concept is based on COVID-19 convalescent plasma. However, rather than using human plasma, XAV-19 is a heterologous swine glyco-humanized polyclonal antibody that targets the spike protein of SARS-CoV-2[L16553,L16558]. The therapy offers three beneficial effects: the ability...
Investigational
Matched Description: … However, rather than using human plasma, XAV-19 is a heterologous swine glyco-humanized polyclonal antibody ... As of July, 2020, the company is conducting a Phase 2 randomized clinical trial to define dosing safety ... Xenothera has partnered with LFB, a pharmaceutical company, to develop XAV-19, and with Nantes University …
Patupilone
Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.
Experimental
Investigational
Matched Description: … Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol. …
Bivatuzumab
Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. [A31688,A31689]
Investigational
Matched Description: … Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. [A31688,A31689] …
Seratrodast
Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
Experimental
Matched Description: … Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. …
Letosteine
Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
Experimental
Matched Description: … Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions …
CSL-689
CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP).
Investigational
Matched Description: … CSL689 is a recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP). …
EA-2353
EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.
Investigational
Matched Description: … EA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway. …
ISB 2001
ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
Investigational
Matched Description: … ISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3. …
Cytidine-5'-Diphosphate
Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate. [PubChem]
Experimental
Matched Description: … A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. …
MAHDL01
MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Investigational
Matched Description: … MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio …
Simmondsia chinensis seed
Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Simmondsia chinensis seed is a plant/plant extract used in some OTC (over-the-counter) products. …
Phellinus linteus mycelium
Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. …
Reynoutria multiflora root
Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. …
Indigofera tinctoria leaf
Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Lonicera confusa flower
Lonicera confusa flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Lonicera confusa flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Platycodon grandiflorus leaf
Platycodon grandiflorus leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Platycodon grandiflorus leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 11176 - 11200 of 11797 in total