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Displaying drugs 14851 - 14875 of 15574 in total

Rolicyclidine

Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.
Experimental
Illicit
Matched Description: … Rolicyclidine (PCPy) is classified as a dissociative anesthetic agent. ... the USA in the 1970s. ... similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in …

SB-649868

SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers).
Investigational
Matched Iupac: … N-{[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl}-1-benzofuran-4 …
Matched Description: … , Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers). ... SB-649868 is under investigation in clinical trial NCT01030939 (Study to Investigate Safety, Tolerability …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

MK-8666

MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).
Investigational
Matched Iupac: … (2S,3S,4R)-8-{[4'-(3-methanesulfonylpropoxy)-2',6'-dimethyl-[1,1'-biphenyl]-3-yl]methoxy}-9-azatricyclo ... [4.4.0.0^{2,4}]deca-1(6),7,9-triene-3-carboxylic acid …
Matched Description: … and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)). ... MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, …

Tigatuzumab

Tigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Tigatuzumab is under investigation in clinical trial NCT00991796 (CS-1008 With Carboplatin/Paclitaxel ... in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small Cell Lung Cancer (NSCLC)). …

Nimacimab

Nimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)).
Investigational
Matched Description: … After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)). ... Nimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 …

Methylsamidorphan

Methylsamidorphan is under investigation in clinical trial NCT01418092 (ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)).
Investigational
Matched Iupac: … cyclopropylmethyl)-3,10-dihydroxy-17-methyl-13-oxo-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2( …
Matched Description: … and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC)). ... Methylsamidorphan is under investigation in clinical trial NCT01418092 (ALK37-007: Evaluation of Safety …

Iscalimab

Iscalimab is under investigation in clinical trial NCT03905525 (Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome).
Investigational
Matched Description: … Doses of CFZ533 in Two Distinct Populations of Patients With Sjögren's Syndrome). ... Iscalimab is under investigation in clinical trial NCT03905525 (Study of Safety and Efficacy of Multiple …

Hypothiocyanite ion

Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX-009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients).
Investigational
Matched Description: … -009 in Healthy Men and Cystic Fibrosis (CF) and Non-CF Bronchiectasis Patients). ... Hypothiocyanite ion is under investigation in clinical trial NCT02598999 (Dose Escalation Study of ALX …

Trelagliptin

Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
Investigational
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)-4-fluorobenzonitrile …
Matched Description: … Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus"). ... Trelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin …

Revusiran

Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)).
Investigational
Matched Description: … Revusiran is under investigation in clinical trial NCT02319005 (ENDEAVOUR: Phase 3 Multicenter Study ... of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy …

RO7284755

RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein. RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or Metastatic Solid Tumors).
Investigational
Matched Description: … RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein ... RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor ... Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or …

Xentuzumab

Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)).
Investigational
Matched Description: … Xentuzumab is under investigation in clinical trial NCT02191891 (Xentuzumab (BI 836845) Plus Afatinib ... in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)). …

Dapansutrile

Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Investigational
Matched Iupac: … 3-methanesulfonylpropanenitrile …
Matched Description: … Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 ... Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee). …

Lazertinib

Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Iupac: … N-{5-[(4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin ... -4-yl)phenyl}prop-2-enamide …
Matched Description: … Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib ... Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer) …

BMS-813160

BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
Investigational
Matched Iupac: … N-[(1R,2S,5R)-5-(tert-butylamino)-2-[(3S)-3-({7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-yl}amino)-2 …
Matched Description: … BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine ... and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC …

Sepofarsen

Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)).
Investigational
Matched Description: … , Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)). ... Sepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety …

Veliflapon

Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).
Investigational
Matched Iupac: … (2R)-2-cyclopentyl-2-{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid …
Matched Description: … Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina). ... Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bentracimab

Bentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure).
Investigational
Matched Description: … Bentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Nadecnemab

Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee).
Investigational
Matched Description: … Nadecnemab is under investigation in clinical trial NCT03956550 (A Study to Examine the Efficacy and ... Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee). …

NRX-1074

NRX-1074 has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Iupac: … -2-yl]formamido}-3-hydroxybutanamide ... (2S,3R)-2-{[(2R)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-2-benzylpyrrolidin …
Matched Description: … NRX-1074 has been used in trials studying the treatment of Schizophrenia. …

Lampalizumab

Lampalizumab has been used in trials studying the treatment of Geographic Atrophy.
Investigational
Matched Description: … Lampalizumab has been used in trials studying the treatment of Geographic Atrophy. …

Placulumab

Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis.
Investigational
Matched Description: … Placulumab has been used in trials studying the treatment of Rheumatoid Arthritis. …

Terbogrel

Terbogrel has been used in trials studying the treatment of Hypertension, Pulmonary.
Investigational
Matched Iupac: … (5E)-6-{3-[(Z)-[(tert-butylamino)(cyanoamino)methylidene]amino]phenyl}-6-(pyridin-3-yl)hex-5-enoic acid …
Matched Description: … Terbogrel has been used in trials studying the treatment of Hypertension, Pulmonary. …

PSI-697

PSI-697 has been used in trials studying the treatment of Scleritis.
Investigational
Matched Iupac: … 2-[(4-chlorophenyl)methyl]-3-hydroxy-7H,8H,9H,10H-cyclohexa[h]quinoline-4-carboxylic acid …
Matched Description: … PSI-697 has been used in trials studying the treatment of Scleritis. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Vatelizumab

Vatelizumab has been used in trials studying the treatment of Ulcerative Colitis.
Investigational
Matched Description: … Vatelizumab has been used in trials studying the treatment of Ulcerative Colitis. …
Displaying drugs 14851 - 14875 of 15574 in total