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Displaying drugs 26 - 50 of 1579 in total
Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 12F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 12F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... capsular antigens of *Streptococcus pneumoniae* serotype 12F individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein
Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 15B individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 15B capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... capsular antigens of *Streptococcus pneumoniae* serotype 15B individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein
Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group y capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... vaccines available: inactivated influenza vaccine (IIV), live attenuated influenza vaccine (LAIV), and recombinant
Matched Categories: … Recombinant influenza vaccines …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 (H3N2) recombinant hemagglutinin antigen …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/02/2018 (H1N1) recombinant hemagglutinin antigen …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Minnesota/41/2019 (H3N2) recombinant hemagglutinin antigen …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen …
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Recombinant human activated protein C (rH-APC) ... Activated protein C …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Recombinant Activated Protein C ... Protein Precursors …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … C1 Inhibitor (Recombinant) ... Recombinant human C1-INH ... C1 Esterase Inhibitor (Recombinant) …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase …
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … B-domain deleted recombinant factor VIII ... Human factor VIII, recombinant B-domain deleted ... Antihemophilic factor recombinant plasma/albumin free …
Matched Description: … Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant ... amino acid, 170 kDa protein [FDA Label]. ... human plasma, rather than being produced through recombinant DNA technology. …
Matched Categories: … Protein Precursors ... Recombinant Proteins …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … ADAMTS13, recombinant-krhn ... Recombinant human adamts13 ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved …
Matched Categories: … Recombinant Proteins …
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Synonyms: … Abatacept recombinant
Matched Description: … It is produced through recombinant DNA technology in mammalian CHO cells. ... [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight ... Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Synonyms: … Glucagon recombinant ... Glucagon (recombinant dna origin) …
Matched Categories: … Protein Precursors …
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin glulisine recombinant ... Insulin Glulisine (recombinant DNA origin) …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... This recombinant hormone differs from native human insulin in that the amino acid asparagine at position …
Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Synonyms: … Recombinant thyrotropin alfa ... Recombinant Human Thyroid Stimulating Hormone …
Matched Description: … Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests …
rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to achieving hemostasis during surgery. ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. Thrombin is used in...
Approved
Investigational
Matched Synonyms: … Recombinant thrombin …
Matched Description: … rhThrombin (recombinant human thrombin) is being developed by ZymoGenetics, Inc. as a general aid to ... ZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from ... The production of recombinant proteins is not dependent on the availability of blood from animals or …
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein
Matched Description: … A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin …
Matched Categories: … Recombinant Proteins ... Narrow Therapeutic Index Drugs …
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant) porcine sequence ... ANTIHEMOPHILIC FACTOR (RECOMBINANT), PORCINE SEQUENCE ... Porcine recombinant factor VIII B-domain truncated …
Matched Description: … autoantibodies neutralize circulating human factor VIII and create a functional deficiency of this procoagulant protein ... Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor ... It is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage …
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Synonyms: … Chorionic gonadotropin (recombinant) …
Matched Description: … Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each …
Nonacog beta pegol is a recombinant coagulation factor IX derivative. It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). Nonacog...
Approved
Investigational
Matched Synonyms: … Coagulation Factor IX (Recombinant), GlycoPEGylated …
Matched Description: … Nonacog beta pegol is a recombinant coagulation factor IX derivative. …
Matched Categories: … Protein Precursors …
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Synonyms: … Recombinant interleukin-11 …
Matched Description: … in Escherichia coli (E. coli) by recombinant DNA technology. ... Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced ... With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids …
Displaying drugs 26 - 50 of 1579 in total