Displaying drugs 3351 - 3375 of 4823 in total
JNJ-39393406
JNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.
Investigational
Matched Iupac: … 3-{3-[(2,2-difluoro-2H-1,3-benzodioxol-5-yl)amino]-5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl}-N,N-dimethylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
JNJ-37822681
JNJ-37822681 has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Iupac: … N-{1-[(3,4-difluorophenyl)methyl]piperidin-4-yl}-6-(trifluoromethyl)pyridazin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Laninamivir
Laninamivir has been used in trials studying the treatment of Influenza.
Investigational
Matched Iupac: … (2R,3R,4S)-4-carbamimidamido-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AMG-900
Investigational
Matched Synonyms: … 1-phthalazinamine, n-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)- …
Matched Iupac: … N-(4-{[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-(4-{[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxy}phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Eleclazine
Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, among others.
Investigational
Matched Description: … Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Acapatamab
Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Caroxazone
Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Withdrawn
Matched Iupac: … 2-(2-oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alagebrium
Alagebrium has been investigated for the treatment and prevention of Aging, Heart Failure, Physical Activity, Diabetic Nephropathy, and Cardiovascular Disease, among others.
Investigational
Matched Iupac: … 4,5-dimethyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
BK-MDA
BK-MDA has been used in trials studying the treatment of Bladder Exstrophy and Urinary Incontinence.
Investigational
Matched Iupac: … 2-amino-1-(2H-1,3-benzodioxol-5-yl)propan-1-one …
MMDA
MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth,...
Experimental
Illicit
Matched Synonyms: … 3-methoxy-methylenedioxyamphetamine ... 3-Methoxy-4,5-methylenedioxyphenylisopropylamine ... 3-Methoxy-alpha-methyl-4,5-methylenedioxyphenethylamine …
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …
Matched Description: … MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant …
Matched Iupac: … 1-(7-methoxy-2H-1,3-benzodioxol-5-yl)propan-2-amine …
Matched Description: … MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant …
Veliparib
Investigational
Matched Iupac: … 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazole-7-carboxamide …
Liarozole
Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Investigational
Matched Iupac: … 6-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CNS-5161
CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Investigational
Matched Iupac: … (E)-N''-[2-chloro-5-(methylsulfanyl)phenyl]-N-methyl-N-[3-(methylsulfanyl)phenyl]guanidine …
Etifoxine
Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an...
Investigational
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Midomafetamine
An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic...
Experimental
Illicit
Investigational
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](methyl)amine …
Methylenedioxyethamphetamine
Experimental
Illicit
Matched Iupac: … [1-(2H-1,3-benzodioxol-5-yl)propan-2-yl](ethyl)amine …
Flubendazole
Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Experimental
Withdrawn
Matched Iupac: … methyl N-[5-(4-fluorobenzoyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Pardoprunox
Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.
Investigational
Matched Iupac: … 7-(4-methylpiperazin-1-yl)-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-05212377
PF-05212377 is under investigation in clinical trial NCT01712074 (Study Evaluating Thesafety and Efficacy of PF-05212377 or Placebo in Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms on Donepezil).
Investigational
Matched Iupac: … 1-(benzenesulfonyl)-2-methyl-4-(piperazin-1-yl)-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
SD118
SD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy for neuropathic pain.
Investigational
ADX-10061
ADX10061 is a potent, selective antagonist of the dopamine D1 receptor. It is developed by Addex Pharmaceuticals for the treatment of nicotine dependence.
Investigational
Matched Iupac: … (5S)-5-(2,3-dihydro-1-benzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol …
SR 121463
SR 121463 is a nonpeptide aquaretic compound with potent selective antagonism of the vasopressin V2 (V1b) receptor subtype. It is a candidate for control of hyponatremia and in the treatment of syndrome of inappropriate secretion of anti-diuretic hormone (SIADH).
Investigational
SR 140333
SR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Investigational
Matched Iupac: … 1-{2-[(3R)-3-(3,4-dichlorophenyl)-1-{2-[3-(propan-2-yloxy)phenyl]acetyl}piperidin-3-yl]ethyl}-4-phenyl ... -1-azabicyclo[2.2.2]octan-1-ium chloride …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ORM-12741
ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … (2S,3S)-3-(methoxymethyl)-3-methyl-17-oxa-7-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),11,13,15 …
Displaying drugs 3351 - 3375 of 4823 in total