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Displaying drugs 4976 - 5000 of 5957 in total

LJP 1082

LJP 1082 is a Toleragen that is designed to shut down the B cells that produce antibodies to ß2 GP1. LJP 1082 is undergoing trial for for the treatment of stroke, deep-vein thrombosis and other conditions associated with antibody-mediated thrombosis. Antibody-mediated thrombosis, also called antiphospholipid syndrome (APS), is a blood...
Investigational
Matched Iupac: … 2-amino-4-({1-[(carboxymethyl)carbamoyl]-2-[(hydroxymethyl)sulfanyl]ethyl}carbamoyl)butanoic acid …
Matched Description: … target of the LJP 1082's clot-promoting antibodies is a small region on a key blood protein called beta 2- …

Danegaptide

Danegaptide has been investigated for the treatment of Focus of Study is STEMI.
Investigational
Matched Iupac: … (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid …

GLPG-0259

GLPG-0259 is under investigation in clinical trial NCT01024517 (GLPG0259 Solid Formulation Bioavailability and Food Effect).
Investigational
Matched Iupac: … 4-[8-({4-[(1S,4S)-5-(propan-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]phenyl}amino)-[1,2,4]triazolo[1,5 ... -a]pyrazin-5-yl]furan-2-carboxamide …

Mazorelvimab

Investigational

4-isothioureidobutyronitrile

Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.
Investigational
Matched Name: … 4-isothioureidobutyronitrile …
Matched Iupac: … 4-(carbamimidoylsulfanyl)butanenitrile …

ATG-101

ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …

Lintuzumab satetraxetan AC-225

Lintuzumab actinium Ac-225 is under investigation in clinical trial NCT00672165 (Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies).
Investigational

Fluorescein lisicol

Fluorescein lisicol has been used in trials studying the diagnostic of Pharmacokinetics, Hepatic Cirrhosis, Hepatitis, Viral, Human, Nonalcoholic Steatohepatitis, and Non-Alcoholic Fatty Liver Disease.
Investigational
Matched Iupac: … 5-({[(5S)-5-carboxy-5-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo ... [8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanamido]pentyl]carbamothioyl}amino)-2-(3,6-dihydroxy-9H-xanthen …

CP-122721

CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.
Investigational
Matched Iupac: … (2S,3S)-N-{[2-methoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine …

OSI-930

OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors. In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small...
Investigational
Matched Iupac: … 3-{[(quinolin-4-yl)methyl]amino}-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide …
Matched Description: … (VEGFR-2). ... inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Flupirtine

Flupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.
Investigational
Matched Iupac: … ethyl N-(2-amino-6-{[(4-fluorophenyl)methyl]amino}pyridin-3-yl)carbamate …

AZD-7762

AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …

Raclopride

Raclopride has been used in trials studying Parkinson Disease.
Investigational
Matched Iupac: … 3,5-dichloro-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-6-methoxybenzamide …

GSI-136

GSI-136 has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … 5-chloro-N-[(2S)-3-ethyl-1-hydroxypentan-2-yl]thiophene-2-sulfonamide …

Muscimol

Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Investigational

Bucillamine

Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
Investigational
Matched Iupac: … (2R)-2-(2-methyl-2-sulfanylpropanamido)-3-sulfanylpropanoic acid …

2-octyl cyanoacrylate

Dermabond has been investigated for the basic science of Wound Healing.
Investigational
Matched Synonyms: … 2-octylcyanoacrylate …
Matched Name: … 2-octyl cyanoacrylate …
Matched Iupac: … octan-2-yl 2-cyanoprop-2-enoate …

Skin-derived ABCB5-positive Mesenchymal Stem cells

Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).
Investigational

Ad-ISF35

Investigational

Acapatamab

Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … ), monoclonal antibody single chain (scfv)2-scfc, bispecific ... hydrolase, prostate specific membrane antigen, psma)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4) …

Iclepertin

Iclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).
Investigational
Matched Synonyms: … [5-(Methylsulfonyl)-2-[(1R)-2,2,2-trifluoro-1-methylethoxy]phenyl][(1R,5R)-1-[5-(trifluoromethyl)-3-isoxazolyl ... Methanone, (5-(methylsulfonyl)-2-((1r)-2,2,2-trifluoro-1-methylethoxy)phenyl)((1r,5r)-1-(5-(trifluoromethyl …

Eldecalcitol

Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
Matched Iupac: … -4-ylidene]ethylidene}-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol ... (1R,2R,3R,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden …

Bradykinin

Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl] ... pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-3-phenylpropanamido]-3-hydroxypropanoyl]pyrrolidin ... -2-yl]formamido}-3-phenylpropanamido]-5-carbamimidamidopentanoic acid …
Matched Description: … Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. …

Belagenpumatucel-L (RH 2)

Investigational
Matched Name: … Belagenpumatucel-L (RH 2) …

BGA002

Investigational
Displaying drugs 4976 - 5000 of 5957 in total