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Displaying drugs 5351 - 5375 of 5601 in total

Plevitrexed

Investigational
Matched Iupac: … )formamido]-4-(1H-1,2,3,4-tetrazol-5-yl)butanoic acid ... (2S)-2-[(4-{[(2,7-dimethyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}-2-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bromopyruvate

Investigational
Matched Synonyms: … 3-bromo-2-oxopropanoic acid …
Matched Iupac: … 3-bromo-2-oxopropanoic acid …

BGT-DTDS

BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) …

Lucanthone

One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.
Investigational
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one ... 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one …
Matched Salts cas: … 548-57-2 …

Batoclimab

Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational

Vapreotide

Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl ... ]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2- …

Vapitadine

Vapitadine is an antihistamine that Barrier Therapeutics is developing as a treatment for allergic reactions of the skin, such as those associated with hives and for the itch associated with atopic dermatitis. An advantage of vapitadine over other antihistamines may be the absence of the sedation, even at high doses.
Investigational
Matched Iupac: … 4',7'-diazaspiro[piperidine-4,2'-tricyclo[8.4.0.0^{3,7}]tetradecane]-1'(10'),3',5',11',13'-pentaene-6 …

GSK-376501

GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus.
Investigational
Matched Iupac: … 1-{[3,5-bis(2-methoxyethoxy)phenyl]methyl}-3-(4-tert-butylphenyl)-1H-indole-2-carboxylic acid …
Matched Description: … GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus. …

Cafedrine

Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Investigational
Matched Iupac: … 7-(2-{[(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]amino}ethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Boldenone

Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.
Illicit
Vet approved

Triciribine

Triciribine has been used in trials studying the treatment of Leukemia, Ovarian Cancer, HER2/Neu Negative, Breast Adenocarcinoma, and Stage IV Breast Cancer, among others.
Investigational
Matched Iupac: … -2-yl}-5-(hydroxymethyl)oxolane-3,4-diol ... (2R,3R,4S,5R)-2-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen …

T-900607

T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.
Investigational
Matched Iupac: … [2-methoxy-5-(2,3,4,5,6-pentafluorobenzenesulfonamido)phenyl]urea …

Tipranavir C-14

Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
Investigational
Matched Iupac: … ]phenyl}-5-(trifluoromethyl)pyridine-2-sulfonamide ... N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl](1-14C)propyl …

Freselestat

Experimental
Investigational
Matched Iupac: … 2-(5-amino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-yl)-N-[(1R,2R)-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl) ... -1-hydroxy-3-methylbutan-2-yl]acetamide …

Telcagepant

Telcagepant has been investigated for the treatment of Migraine. It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the...
Investigational
Matched Iupac: … N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-{2-oxo-1H,2H,3H-imidazo …
Matched Salts cas: … 953077-35-5 …

CEP-37440

CEP-37440 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … -2-yl]amino}pyrimidin-4-yl)amino]-N-methylbenzamide ... 2-[(5-chloro-2-{[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen …

Mitiglinide

Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Investigational
Matched Iupac: … (2S)-4-[(3aR,7aS)-octahydro-1H-isoindol-2-yl]-2-benzyl-4-oxobutanoic acid …
Matched Description: … Mitiglinide is a drug for the treatment of type 2 diabetes. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Misonidazole

Misonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
Investigational
Matched Iupac: … 1-methoxy-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol …

Pimonidazole

Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.
Investigational
Matched Iupac: … 1-(2-nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol …

Uridine

Experimental
Investigational
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …

Alfimeprase

Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational

Tinodasertib

Investigational

Merestinib

Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl- ... 2-oxo-1,2-dihydropyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Amcasertib

Amcasertib is under investigation in clinical trial NCT02483247 (A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer).
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-oxo-5-(2-phenyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol …

Sitravatinib

Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … N'1-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl …
Displaying drugs 5351 - 5375 of 5601 in total