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Displaying drugs 1701 - 1725 of 3792 in total
AQ-13
AQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Investigational
OT-15
Investigational
IDM-1
IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc.
Investigational
Matched Name: … IDM-1 …
Matched Description: … IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. …
Matched Description: … IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. …
PX-12
PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor growth in animal models. Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment...
Investigational
Matched Synonyms: … 1-Methylpropyl-2-imidazolyl disulfide …
Matched Description: … PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), ... Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … PX-12 (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), ... Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ADH-1
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide …
Matched Name: … ADH-1 …
Matched Description: … Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells ... ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic ... Company also completed patient enrollment in our single-agent Phase Ib/II and Phase II trials of ADH-1. …
Matched Name: … ADH-1 …
Matched Description: … Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells ... ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic ... Company also completed patient enrollment in our single-agent Phase Ib/II and Phase II trials of ADH-1. …
ING-1
ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton epithelial cell adhesion molecule (EpCAM) glycoprotein that is expressed in high levels on most adenocarcinomas. It is an attractive target for immunotherapy.
Investigational
Matched Name: … ING-1 …
Matched Description: … ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton …
Matched Description: … ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton …
MC-16
Investigational
Matched Synonyms: … (+)-5-chloro-1-ethyl-3-(2-hydroxy-3-methoxybenzyl)-2-oxoindolin-3-yl dimethylcarbamate …
Matched Iupac: … 5-chloro-1-ethyl-3-[(2-hydroxy-3-methoxyphenyl)methyl]-2-oxo-2,3-dihydro-1H-indol-3-yl N,N-dimethylcarbamate …
Matched Iupac: … 5-chloro-1-ethyl-3-[(2-hydroxy-3-methoxyphenyl)methyl]-2-oxo-2,3-dihydro-1H-indol-3-yl N,N-dimethylcarbamate …
X-165
Investigational
Matched Synonyms: … (R)-N-(1-(1-(1H-indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4,5]decan-8-yl)-3-methyl-1-oxobutan …
SGN-1
SGN-1 is a genetically modified strain of Salmonella enterica comprising methioninase.
Investigational
Matched Name: … SGN-1 …
Matched Description: … SGN-1 is a genetically modified strain of _Salmonella enterica_ comprising methioninase. …
Matched Description: … SGN-1 is a genetically modified strain of _Salmonella enterica_ comprising methioninase. …
CP-12
Investigational
Matched Synonyms: … PROLYL-L-SERYL-L-HISTIDYL-L-ISOLEUCYL-L-SERYL-L-LYSYL-L-TYROSYL-L-ISOLEUCYL-L-LEUCYL- L-ARGINYL-L-TRYPTOPHANYL-L-ARGINYL-L-PROLYL-L-LYSYL), CYCLO (1- …
UV1
UV1 is a cancer vaccine consisting of p719-20, p728, and p725 synthetic peptides representing fragments of the hTERT subunit
Investigational
VGV-1
VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral therapy.
Investigational
Matched Name: … VGV-1 …
Matched Description: … VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral …
Matched Description: … VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral …
IDD-1
Lipids promote the fusion of liposomes to cells. Eladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor antigens and then reinjected into the subject. As with other monoclonal antibodies, this process stimulates an immune response to a particular disease-related antigen.
Investigational
Matched Name: … IDD-1 …
Matched Description: … Eladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor …
Matched Description: … Eladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor …
MKC-1
Investigational
Matched Name: … MKC-1 …
Matched Iupac: … 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
EC-17
Folate Fitc has been used in trials studying the diagnostic of Ovarian Cancer.
Investigational
Matched Iupac: … (2S)-2-[1-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}phenyl)-N-{2-[({3',6'-dihydroxy-3 …
Z-160
Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.
Investigational
Matched Synonyms: … 1-(4-Benzhydryl-piperazin-1-yl)-3,3-diphenylpropan-1-one ... 1-(4-Benzhydrylpiperazin-1-yl)-3,3-Diphenylpropan-1-one …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GB-13
GB-13 is a genetically engineered recombinant protein consisting of an IL13Ra2-targeted genetically engineered mutant of IL-13 and PE4E, a derivative of Pseudomonas exotoxin A.
Investigational
LIS-1
LIS-1 is an immunoglobulin G (IgG) polyclonal antibody that binds to human T cells.
Investigational
Matched Name: … LIS-1 …
Matched Description: … LIS-1 is an immunoglobulin G (IgG) polyclonal antibody that binds to human T cells. …
Matched Description: … LIS-1 is an immunoglobulin G (IgG) polyclonal antibody that binds to human T cells. …
Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Matched Iupac: … (5Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-3-oxocyclopentyl]hept-5-enoic acid …
Nevanimibe
Nevanimibe is under investigation in clinical trial NCT03053271 (A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome).
Investigational
Matched Iupac: … 1-[2,6-bis(propan-2-yl)phenyl]-3-({1-[4-(dimethylamino)phenyl]cyclopentyl}methyl)urea …
Azasetron
Investigational
Matched Iupac: … N-{1-azabicyclo[2.2.2]octan-3-yl}-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cobamamide
Cobamamide is one of the active forms of vitamin B12 that is also known as adenosylcobalamin or dibencozide. This drug is available as a nutritional supplement to prevent vitamin B12 deficiency.
Vitamin B12 is a collective term for these variously substituted corrinoids. The principal biochemical participants are two coenzyme forms...
Nutraceutical
Matched Iupac: … 37,45}]heptatetraconta-2(47),3,5,7,27,29(44),32,34(45),37,39(43)-decaene-2,43,44,45-tetrakis(ylium)-1,1,1 ... cobaltadodecacyclo[27.14.1.1^{1,34}.1^{2,9}.1^{10,13}.0^{1,26}.0^{3,8}.0^{23,27}.0^{25,42}.0^{32,44}.0 ... (10S,12R,13S,17R,23R,24R,25R,30S,35S,36S,40S,41S,42R,46R)-1-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl) ... 15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
MB-102 CD123 CAR
MB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
Investigational
Adze-1.17-CD40L
Investigational
Displaying drugs 1701 - 1725 of 3792 in total