Search Results | DrugBank Online

Displaying drugs 2651 - 2675 of 2809 in total

AICA ribonucleotide

5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has been used clinically to treat and protect against cardiac ischemic injury. The drug was first used in the 1980s as...

Experimental

Investigational

5'-Guanosine-Diphosphate-Monothiophosphate

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.

Experimental

N6-Benzyl Adenosine-5'-Diphosphate

Experimental

p1-(5'-adenosyl)p5-(5'-thymidyl)pentaphosphate

Experimental

2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE

Experimental

Rapastinel

Rapastinel has been used in trials studying the treatment of Depressive Disorder, Major and Obsessive-Compulsive Disorder (OCD).

Investigational

AZD-4818

AZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD).

Investigational

Rotigaptide

Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.

Investigational

Tyrosyladenylate

Experimental

Guanosine tetraphosphate

Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids...

Experimental

8-Bromoadenosine-5'-Diphosphate

Experimental

Velusetrag

Velusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research...

Investigational