Displaying drugs 2901 - 2925 of 3184 in total
5'-S-[2-(decylamino)ethyl]-5'-thioadenosine
Experimental
Matched Name: … 5'-S-[2-(decylamino)ethyl]-5'-thioadenosine …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-({[2-(decylamino)ethyl]sulfanyl}methyl)oxolane-3,4-diol …
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-({[2-(decylamino)ethyl]sulfanyl}methyl)oxolane-3,4-diol …
2-[(2-NAPHTHYLSULFONYL)AMINO]ETHYL DIHYDROGEN PHOSPHATE
Experimental
Matched Name: … 2-[(2-NAPHTHYLSULFONYL)AMINO]ETHYL DIHYDROGEN PHOSPHATE …
Matched Iupac: … [2-(naphthalene-2-sulfonamido)ethoxy]phosphonic acid …
Matched Iupac: … [2-(naphthalene-2-sulfonamido)ethoxy]phosphonic acid …
Dipropyl-4-hydroxytryptamine
Dipropyl-4-hydroxytryptamine is the 4-hydroxyl analog of dipropyltryptamine (DPT). Dipropyl-4-hydroxytryptamine was first synthesized by Alexander Shulgin. This agent and its properties haven't been fully elucidated.
Experimental
Matched Synonyms: … 3-[2-(Dipropylamino)ethyl]-1H-indol-4-ol …
Matched Iupac: … 3-[2-(dipropylamino)ethyl]-1H-indol-4-ol …
Matched Description: … This agent and its properties haven't been fully elucidated. …
Matched Iupac: … 3-[2-(dipropylamino)ethyl]-1H-indol-4-ol …
Matched Description: … This agent and its properties haven't been fully elucidated. …
NSC-663284
NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.
Investigational
Matched Synonyms: … 5,8-quinolinedione, 6-chloro-7-((2-(4-morpholinyl)ethyl)amino)- …
Matched Iupac: … 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}-5,8-dihydroquinoline-5,8-dione …
Matched Iupac: … 6-chloro-7-{[2-(morpholin-4-yl)ethyl]amino}-5,8-dihydroquinoline-5,8-dione …
Pyrimethamine
One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine ... 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine …
Matched Description: … One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis …
Matched Categories: … Folic Acid Antagonists ... Antiparasitic Products, Insecticides and Repellents ... artesunate, sulfalene and pyrimethamine ... artesunate, sulfadoxine and pyrimethamine …
Matched Description: … One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis …
Matched Categories: … Folic Acid Antagonists ... Antiparasitic Products, Insecticides and Repellents ... artesunate, sulfalene and pyrimethamine ... artesunate, sulfadoxine and pyrimethamine …
N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide
Experimental
Matched Name: … N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide …
Matched Iupac: … N-[(1S)-1-(dimethylcarbamoyl)-2-phenylethyl]-2-oxo-N'-[2-(pyridin-2-yl)ethyl]butanediamide …
Matched Iupac: … N-[(1S)-1-(dimethylcarbamoyl)-2-phenylethyl]-2-oxo-N'-[2-(pyridin-2-yl)ethyl]butanediamide …
ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE
Experimental
Matched Name: … ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE …
Matched Iupac: … {[(Z)-[1-(ethylsulfanyl)-2-phenylethylidene]amino]oxy}sulfonic acid …
Matched Iupac: … {[(Z)-[1-(ethylsulfanyl)-2-phenylethylidene]amino]oxy}sulfonic acid …
N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE
Experimental
Matched Name: … N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE …
Matched Iupac: … N-[2-(4-sulfamoylphenyl)ethyl]acetamide …
Matched Iupac: … N-[2-(4-sulfamoylphenyl)ethyl]acetamide …
(2S)-2-({4-[(2S)-1-(2-Amino-4-oxo-1,4-dihydro-6-quinazolinyl)-3-{[2-({(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}amino)-2-oxoethyl]amino}-2-hydroxy-2-propanyl]benzoyl}ami no)pentanedioic acid
Experimental
Matched Name: … }ami no)pentanedioic acid ... dihydroxy-5-[(phosphonooxy)methyl]tetrahydro-2-furanyl}amino)-2-oxoethyl]amino}-2-hydroxy-2-propanyl]benzoyl …
Matched Iupac: … phosphonooxy)methyl]oxolan-2-yl]carbamoyl}methyl)amino]-2-hydroxypropan-2-yl]phenyl}formamido)pentanedioic acid …
Matched Iupac: … phosphonooxy)methyl]oxolan-2-yl]carbamoyl}methyl)amino]-2-hydroxypropan-2-yl]phenyl}formamido)pentanedioic acid …
(7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
Experimental
Matched Name: … Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
Matched Iupac: … diazatricyclo[6.3.0.0^{2,6}]undeca-2(6),8,10-trien-10-yl}-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL] …
Phylloquinone
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Synonyms: … alpha-Phylloquinone …
Matched Description: … FDA prior to 1955. ... precursors to coagulation factors II, VII, IX, and X. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates …
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition …
Matched Description: … FDA prior to 1955. ... precursors to coagulation factors II, VII, IX, and X. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates …
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition …
BR101801
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
GSK-269962A
GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.
Investigational
Matched Synonyms: … Benzamide, n-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)- ... N-(3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1h-imidazo(4,5-c)pyridin-6-yl)oxy)phenyl)-4-(2-(4-morpholinyl …
Matched Iupac: … N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin …
Matched Description: … GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.[A253012] …
Matched Iupac: … N-(3-{[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin …
Matched Description: … GSK-269962A is a Rho kinase (ROCK) inhibitor with both ROCK1 and ROCK2 affinity.[A253012] …
AZD-5153
Investigational
Matched Synonyms: … 2-piperazinone, 4-(2-(4-(1-(3-methoxy-1,2,4-triazolo(4,3-b)pyridazin-6-yl)-4-piperidinyl)phenoxy)ethyl …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin …
Matched Iupac: … (3R)-4-{2-[4-(1-{3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidin-4-yl)phenoxy]ethyl}-1,3-dimethylpiperazin …
Gimatecan
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline ... 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy …
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Dimenhydrinate
Dimehydrinate was first described in the literature in 1949, and patented in 1950. Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and...
Approved
Matched Synonyms: … β-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine …
Matched Iupac: … 8-chloro-1,3-dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione; [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Description: … [A1539] Dimenhydrinate was granted FDA approval on 31 May 1972.[L32975] ... Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. ... , is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness. …
Matched Categories: … Aminoalkyl Ethers …
Matched Iupac: … 8-chloro-1,3-dimethyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione; [2-(diphenylmethoxy)ethyl]dimethylamine …
Matched Description: … [A1539] Dimenhydrinate was granted FDA approval on 31 May 1972.[L32975] ... Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. ... , is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness. …
Matched Categories: … Aminoalkyl Ethers …
Calcitriol
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Synonyms: … 1-alpha-25-Dihydroxyvitamin D3 …
Matched Description: … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated ... There is also evidence that calcitriol modulates the action of cytokines and may regulate immune and ... chronic renal dialysis, and osteoporosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... Diet, Food, and Nutrition ... Vitamin D and Analogues ... Skin and Mucous Membrane Agents …
Matched Description: … In addition to promoting fatty acid synthesis and inhibiting lipolysis, calcitriol has been demonstrated ... There is also evidence that calcitriol modulates the action of cytokines and may regulate immune and ... chronic renal dialysis, and osteoporosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... Diet, Food, and Nutrition ... Vitamin D and Analogues ... Skin and Mucous Membrane Agents …
Nefazodone
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Synonyms: … 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID
Experimental
Matched Name: … 7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID …
Betaxolol
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Zandelisib
Investigational
Matched Synonyms: … amine, 4-(2-(difluoromethyl)-1h-benzimidazol-1-yl)-n-(1,1-dimethyl-2-(2-(1-methyl-4-piperidinyl)phenyl)ethyl ... 4-(2-(difluoromethyl)benzimidazol-1-yl)-n-(1,1-dimethyl-2-(2-(1-methyl-4-piperidyl)phenyl)ethyl)-6-morpholino …
{4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid
Experimental
Matched Name: … Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid …
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid …
Matched Iupac: … benzothiazol-2-yl)-2-(1H-1,2,3-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl}difluoromethyl)phosphonic acid …
Rineterkib
Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … 3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl ... 3s,4s)-3-fluoro-4-hydroxycyclohexyl)-2-pyrazinyl)-n-((1s)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl …
Matched Iupac: … 3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
Matched Iupac: … 3S,4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl …
Matched Description: … investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and …
(E)-(S)-4-[(S)-4-METHYL-2-((S)-3-METHYL-2{(S)-2-[(5-METHYL-ISOXAZOLE-3- CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID ETHYL ESTER
Experimental
Matched Name: … ETHYL ESTER ... CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-PENTANOYLAMINO]-5-((S)-2- OXO-PYRROLIDIN-3-YL)-PENT-2-ENOIC ACID …
Matched Iupac: … ethyl (2E,4S)-4-[(2S)-4-methyl-2-[(2S)-3-methyl-2-[(2S)-2-[(5-methyl-1,2-oxazol-3-yl)formamido]propanamido …
Matched Iupac: … ethyl (2E,4S)-4-[(2S)-4-methyl-2-[(2S)-3-methyl-2-[(2S)-2-[(5-methyl-1,2-oxazol-3-yl)formamido]propanamido …
Displaying drugs 2901 - 2925 of 3184 in total