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Displaying drugs 3501 - 3525 of 4208 in total
Approved
Matched Synonyms: … L-DPPG-Na …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Description: … effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation ... However, it has a negligible effect on altering the development and progression of breast cancer itself ... [label] The most common causes of osteoporosis include postmenopausal deficiency of estrogen and age-related …
Matched Salts name: … Raloxifene Hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Apo-raloxifene ... Act Raloxifene ... Raloxifene Hydrochloride
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … It also has a number of unique characteristics that have led to its increased use in the last two decades ... to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost ... , and as an inhibitor of serotonin and norepinephrine uptake. …
Matched Salts name: … Methadone hydrochloride
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Apo-methadone ... ABL METAPAD COMPRIMIDOS 10 MG ... Methadone Hydrochloride
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear,...
Approved
Investigational
Matched Description: … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, ... mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and ... An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological …
Matched Salts name: … Papaverine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Papaverine and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … Papaverine Hydrochloride ... PAPAVERINE HYDROCHLORIDE ... Papaverine Hydrochloride Injection USP …
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Description: … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative ... Initially introduced in 1983 in Japan as treatment for neurological conditions such as anxiety and sleep ... and skeletal muscle relaxant properties. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Synonyms: … Antineoplaston A 10 …
Matched Name: … Antineoplaston A10
Matched Description: … Liver Cancer, and Kidney Cancer, among others. ... Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … DILACTONE ACTINOMYCIN D ACID ... ANA-conjugated dactinomycin nanoemulsion ... CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than ... As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. ... A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... Nucleic Acid Synthesis Inhibitors ... Protein Synthesis Inhibitors …
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. Until 2017, midecamycin was still under the list of approved...
Experimental
Matched Synonyms: … Espinomycin A ... Medemycin A1 ... Medecamycin A1
Matched Description: … In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position ... Midecamycin is a naturally occurring 16-membered macrolide[A33072] that fits under the category of acetoxy-substituted …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … in a pH-dependent manner ... GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched International brands: … Protemp
Matched Iupac: … [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid
Matched Description: … [A251885] Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral ... , Norway and Australia. ... It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. …
Matched Products: … METAMIZOL HEXAL INJEKT LSG ... METAMIZOLO SODICO ABC ... METAMIZOL ABZ 500MG TAB …
This solid compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. This substance targets the protein interleukin-2.
Experimental
Matched Synonyms: … Methyl N-{[(3R)-1-carbamimidoyl-3-piperidinyl]acetyl}-4-(phenylethynyl)-L-phenylalaninate …
Matched Description: … This substance targets the protein interleukin-2. ... These are organic compounds containing a 1,2-diphenylethylene moiety. ... The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. …
Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed by sulfonation and neutralization. It is available in OTC products as an active ingredient for the treatment of skin disorders...
Approved
Matched Description: … , psoriasis and boils as it is thought to exhibit anti-inflammatory, antibacterial and antimycotic properties ... the oil followed by sulfonation and neutralization. ... It is available in OTC products as an active ingredient for the treatment of skin disorders such as eczema …
Matched Products: … MG217 First Aid Drawing Salve ... Solutio Cordes 0,5% - dermatologische Lösung …
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
Matched Description: … form pills approved in United States and Europe however it is not available in the US by itself. ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. ... Dienogest is commonly marketed as Visanne, Natazia and Qlaira. …
Matched Mixtures name: … Estradiol Valerate and Estradiol Valerate/Dienogest ... Estradiol Valerate and Estradiol Valerate/Dienogest …
Matched Categories: … dienogest and estrogen ... dienogest and estradiol ... dienogest and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched International brands: … Xi An Lin
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm ... [A178579] Sotalol was first approved as an oral tablet on 30 October 1992. …
Matched Salts name: … Sotalol hydrochloride
Matched Categories: … sotalol and acetylsalicylic acid ... sotalol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Sotalol Hydrochloride AF ... Sotalol Hydrochloride ... Sotalol hydrochloride
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Apo-colesevelam ... Colesevelam Hydrochloride ... Colesevelam hydrochloride
Experimental
Matched Name: … Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam
Investigational
Matched Synonyms: … Designed ankyrin repeat protein (MP0250) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Recombinant Proteins
Investigational
Matched Synonyms: … Axl fc fusion protein avb-s6-500 ... AVB-S6-500 …
AMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human Dok-7 protein. It is under investigation for the treatment of Dok-7-associated myasthenia.
Investigational
Matched Synonyms: … Adeno-associated virus serotype 9 vector encoding the Dok7 protein
Matched Name: … AMP-101 …
Matched Description: … Dok-7 protein. ... AMP-101 is a gene therapy comprising an adeno-associated virus type 9 (AAV9) vector encoding the human …
Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse. The...
Approved
Illicit
Withdrawn
Matched Description: … hydrochloride, a metamfetamine salt. ... Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine ... Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem …
Matched Salts name: … Metamfetamine hydrochloride
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Drugs that are Mainly Renally Excreted …
Matched Products: … Methamphetamine Hydrochloride
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … The product contains the identical amino acid sequence of isolated natural erythropoietin and has the ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using ... The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins ... Proteins
Matched Products: … EXETIN-A ... Binocrit 2,000 IU/1 ml solution for injection in a pre-filled syringe ... Binocrit 10 000 IU/1 ml solution for injection in a pre-filled syringe …
Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Description: … M1 and M3. ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's ... Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors …
Matched Salts name: … Cevimeline hydrochloride
Matched Categories: … Sulfur Compounds ... Drugs that are Mainly Renally Excreted …
Matched Products: … Cevimeline Hydrochloride
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Salts name: … Rimantadine hydrochloride
Matched Categories: … Influenza A M2 Protein Inhibitor ... Nucleic Acid Synthesis Inhibitors ... M2 Protein Inhibitors …
Matched Products: … Rimantadine Hydrochloride
Displaying drugs 3501 - 3525 of 4208 in total