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Displaying drugs 351 - 358 of 358 in total

Sinefungin

Sinefungin is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar. The proteins that adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and modification methylase RsrI.
Experimental
Matched Description: … This compound belongs to the purine nucleosides and analogues. ... adenosyl-ornithine target include RdmB, modification methylase TaqI, rRNA (adenine-N6-)-methyltransferase, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

KW-7158

KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the bladder). The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels...
Investigational
Matched Description: … "urinary incontinence" associated with bladder overactivity (involuntary abnormal contraction of the ... a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and ... bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and …

Calanolide A

Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. Both drugs are being developed by Sarawak Pharmaceuticals. A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared...
Investigational

Toloxatone

Toloxatone is an antidepressant agent, the first ever use of which was in France, 1984. It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) .
Experimental
Matched Description: … It acts as a selective and reversible inhibitor of monoamine oxidase-A (MOA) [L1388]. …

Paramethasone

A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Categories: … Hyperglycemia-Associated Agents ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Dexamethasone isonicotinate

Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Vet approved
Matched Description: … Its unintended mineralocorticoid action may cause salt and water retention. ... anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and …
Matched Categories: … Hyperglycemia-Associated Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Mometasone

Mometasone is a corticosteroid not currently used in medical products. Mometasone furoate however, is still in use.
Experimental
Matched Categories: … Hyperglycemia-Associated Agents ... indacaterol and mometasone ... indacaterol, glycopyrronium bromide and mometasone …

Rifalazil

Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Displaying drugs 351 - 358 of 358 in total