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Displaying drugs 726 - 750 of 925 in total
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Matched Synonyms: … (2S)-alpha-Leucine ... (2S)-alpha-2-Amino-4-methylvaleric acid …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … (S)-alpha-Methyltyrosine ... (-)-alpha-Methyl-L-tyrosine …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -aspartyl-l-.alpha. ... -glutamyl-l-seryl-l-asparaginyl-l-isoleucyl-l-seryl-l-phenylalanyl-l-lysyl-l-.alpha.-glutamyl- ... L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l-.alpha
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … N-alpha-L-acetyl-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Synonyms: … 16-alpha-Hydroxyestradiol ... 1,3,5(10)-Estratriene-3,16-alpha,17beta-triol …
Matched Description: … A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the …
Matched Categories: … Genito Urinary System and Sex Hormones ... Natural and Semisynthetic Estrogens, Plain ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Experimental
Matched Synonyms: … (+/-)-alpha-amino-4-hydroxybenzeneacetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and ... Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Synonyms: … alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide …
Matched Description: … belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ... 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid …
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-Phospho-alpha-D-ribose 1-diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Experimental
Matched Name: … Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam …
Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …
Experimental
Matched Name: … N7-(5'-Phospho-alpha-ribosyl)-2-hydroxypurine …
Experimental
Matched Name: … 4,6-dideoxy-4-amino-alpha-D-glucose …
Experimental
Matched Name: … N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide …
Investigational
Matched Synonyms: … .,5.alpha.,22.alpha.,25r)-26-(.beta.-d-glucopyranosyloxy)-22-hydroxyfurostan-3-yl o-.beta. …
Experimental
Matched Synonyms: … alpha-Hydroxy-gamma-(methylthio)butyric acid ... alpha-Hydroxy-gamma-(methylmercapto)butyric acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Florfenicol is a fluorinated synthetic analog of thiamphenicol.
Experimental
Vet approved
Matched Synonyms: … D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide …
Investigational
Matched Synonyms: … Alpha-quinidine …
Solnatide has been used in trials studying the treatment of Acute Lung Injury.
Investigational
Matched Synonyms: … L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-glutamylglycyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … (.alpha.3,.alpha.6,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo …
Matched Description: … hardening of skin and subcutaneous tissues. ... vascularity in the central nervous system and the body. ... It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal …
Experimental
Matched Synonyms: … (alpha-Aminoadipyl)-cys-val ... L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … 1-118-signal regulatory protein .alpha. …
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … alpha-difluoromethylornithine …
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... for the treatment of African trypanosomiasis and hirsutism, respectively, but has since been discontinued …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 726 - 750 of 925 in total