Displaying drugs 851 - 875 of 1265 in total
Agomelatine
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational
Matched Description: … Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors ... Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines …
Matched Products: … AGOMELATIN BETA 25MG FTA …
Matched Products: … AGOMELATIN BETA 25MG FTA …
Willardiine
Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental
Matched Synonyms: … beta-(2,4-Dihydroxypyrimidin-1-yl)alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cryptoxanthin
Experimental
Matched Synonyms: … beta-Cryptoxanthin …
Matched Categories: … Diet, Food, and Nutrition …
Matched Categories: … Diet, Food, and Nutrition …
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody ... receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody …
Matched Description: … Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Experimental
Matched Name: … 3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide …
Lactulose
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID
Experimental
Matched Name: … {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID …
Anvatabart opadotin
Investigational
Matched Synonyms: … tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody ... monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal Amab788 κ-chain, dimer, 121,121′-dioxime …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-beta-D-glucopyranosylacetamide
Experimental
Matched Synonyms: … 1-N-acetyl-beta-D-glucosamine …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Methyl beta-L-fucopyranoside
Experimental
Matched Synonyms: … Methyl 6-deoxy-beta-L-galactopyranoside …
Matched Name: … Methyl beta-L-fucopyranoside …
Matched Name: … Methyl beta-L-fucopyranoside …
Glycyrrhizic acid
Glycyrrhizic acid is extracted from the root of the licorice plant; Glycyrrhiza glabra. It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. Glycyrrhizic...
Approved
Experimental
Matched Synonyms: … 18-beta-Glycyrrhizic acid …
Matched Description: … It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium ... [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Matched Description: … It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium ... [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy …
beta-D-glucuronic acid
Experimental
Matched Synonyms: … beta-D-Glucopyranuronic acid …
Matched Name: … beta-D-glucuronic acid …
Matched Name: … beta-D-glucuronic acid …
Paroxetine
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Description: … of serotonin reuptake and has little effect on other neurotransmitters. ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. ... uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and …
Matched Products: … PAROXETIN BETA 10MG ... PAROXETIN BETA 20MG ... PAROXETIN BETA 30MG …
Matched Products: … PAROXETIN BETA 10MG ... PAROXETIN BETA 20MG ... PAROXETIN BETA 30MG …
2'-fluoro-5-ethylarabinosyluracil
2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.
Investigational
Matched Synonyms: … 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil ... 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb ... XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …
Cytarabine
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine ... Cytosine-1-beta-D-arabinofuranoside ... 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone …
Matched Description: … It also has antiviral and immunosuppressant properties. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … It also has antiviral and immunosuppressant properties. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Nucleic Acids, Nucleotides, and Nucleosides …
Crovalimab
Crovalimab is under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria).
Investigational
Matched Synonyms: … Complement c5 inhibitory humanized recycling monoclonal antibody (rg-6107 ) …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
Matched Description: … under investigation in clinical trial NCT03157635 (Study to Assess Safety, Efficacy, Pharmacokinetics, and ... Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria …
beta-D-glucose 6-phosphate
Experimental
Matched Synonyms: … beta-D-glucose-6-phosphate ... beta-D-Glucose 6-phosphic acid ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate …
Matched Name: … beta-D-glucose 6-phosphate …
Begelomab
Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … COMPLEXING PROTEIN 2, ADCP2, TP103, T CELL ACTIVATION ANTIGEN CD26, CD26)), MUS MUSCULUS MONOCLONAL ANTIBODY …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Begelomab is a murine monoclonal antibody against CD26. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
KITE-222
Investigational
Matched Synonyms: … An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived …
1,4-dithio-beta-D-glucopyranose
Experimental
Matched Synonyms: … 1,4-deoxy-1,4-dithio-beta-D-glucopyranose …
Matched Name: … 1,4-dithio-beta-D-glucopyranose …
Matched Name: … 1,4-dithio-beta-D-glucopyranose …
Displaying drugs 851 - 875 of 1265 in total