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Displaying drugs 901 - 925 of 1333 in total
Pentaglyme
Experimental
ZM-39923
ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).
Investigational
Matched Description: … ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2). …
Lazertinib
Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Investigational
Matched Categories: … Protein Kinase Inhibitors ... Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Aprinocarsen
Aprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha.
Investigational
Matched Description: … Aprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha. …
Matched Categories: … Protein Kinase C, antagonists & inhibitors …
Matched Categories: … Protein Kinase C, antagonists & inhibitors …
EI-1071
EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
Investigational
Matched Description: … EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor. …
Ingavirin
Ingavirin has been used in trials studying the treatment of Influenza and Common Cold.
Investigational
Rociletinib
Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Investigational
Matched Categories: … Protein Kinase Inhibitors ... Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Alisertib
Alisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
Investigational
Matched Description: … Alisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms …
Matched Categories: … Protein Kinase Inhibitors …
Matched Categories: … Protein Kinase Inhibitors …
Perifosine
Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition.
Investigational
Matched Description: … Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase …
LY-294002
Specific inhibitor of phosphatidylinositol 3-kinase.
Experimental
Matched Description: … Specific inhibitor of phosphatidylinositol 3-kinase. …
SGX-523
A MET receptor tyrosine kinase inhibitor.
Investigational
Matched Description: … A MET receptor tyrosine kinase inhibitor. …
Cenisertib
Cenisertib is an aurora kinase inhibitor.
Investigational
Matched Description: … Cenisertib is an aurora kinase inhibitor. …
Tricetin
Experimental
Indium In-111 imciromab pentetate
Indium In-111 imciromab pentetate is a mouse monoclonal antibody labelled with the radioisotope Indium-111 which was used for cardiac imaging under the trade name Myoscint, but was withdrawn in 1993.
Withdrawn
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Description: … Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for …
Sinbaglustat
Investigational
Cediranib
The novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment of cancer.
Investigational
Matched Description: … highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase …
Matched Categories: … Protein Kinase Inhibitors ... Tyrosine Kinase Inhibitors ... Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors …
Matched Categories: … Protein Kinase Inhibitors ... Tyrosine Kinase Inhibitors ... Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors …
3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone
Experimental
Matched Categories: … Tyrosine Kinase Inhibitors …
Savolitinib
Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.
Investigational
Matched Categories: … Tyrosine Kinase Inhibitors …
Icotinib
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational
Matched Description: … Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ( …
Matched Categories: … Protein Kinase Inhibitors ... Tyrosine Kinase Inhibitors ... Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
Matched Categories: … Protein Kinase Inhibitors ... Tyrosine Kinase Inhibitors ... Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors …
TG-100801
TG100801 is a topically applied kinase inhibitor in macular degeneration patients. It is administered noninvasively as an eye drop and is designed to suppress VEGF mediated leakage and additional kinase targets associated with inflammation, edema, and angiogenesis which are the pathological hallmarks of AMD and other back of the eye...
Investigational
Matched Description: … TG100801 is a topically applied kinase inhibitor in macular degeneration patients. ... administered noninvasively as an eye drop and is designed to suppress VEGF mediated leakage and additional kinase …
XL019
XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.
Investigational
Matched Description: … XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. …
Penthienate
Experimental
Displaying drugs 901 - 925 of 1333 in total