Savolitinib

DB12048InvestigationalSmall molecule

Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.

Mechanism: Pharmacologically active on Hepatocyte growth factor receptor
Curator reviewed
Formula / weight: C₁₇H₁₅N₉ · 345.37 g/mol (avg)
Also known as: Volitinib
Code names: AZD-6094 · HMPL-504

Resolves to

Compound

UNII2A2DA6857RCAS1313725-88-0ChEMBLCHEMBL3334567PubChem68289010

Structure

InChIKeyXYDNMOZJKOGZLS-NSHDSACASA-NSMILESC[C@H](N1N=NC2=NC=C(N=C12)C1=CN(C)N=C1)C1=CN2C=CN=C2C=C1

Targets

P08581MET

What you can answer from here — as of July 31, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

27Drug interactionsStructured to mechanism, not free text

42Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Savolitinib, and which of those have an active Phase 3 trial?

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