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Displaying drugs 226 - 250 of 14784 in total

Vitamin A

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...

Approved

Nutraceutical

Vet approved

Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... It is enriched in the liver, egg yolks, and the fat component of dairy products. …
Matched Mixtures name: … Vitamin A and D ... A and D Ointment ... Calci A and D Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …

Barium sulfate

Barium sulfate is an inorganic compound with the chemical formula BaSO4 . Barium sulfate occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield . This drug is used as a contrast agent in...

Approved

Matched Description: … and high level of clearance from the body [FDA label]. ... Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent ... It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation …
Matched Categories: … Diagnostic Uses of Chemicals ... X-Ray Contrast Media, Non-Iodinated …

Rupatadine

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...

Approved

Matched Description: … adult use and liquid formulation for pediatric use. ... Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is ... used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria …
Matched Categories: … Histamine H1 Antagonists, Non-Sedating …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...

Approved

Investigational

Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... However, it continues to be used in the treatment of Brugada syndrome, short QT syndrome and idiopathic …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Quinine and stereoisomer …

Mifamurtide

Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...

Approved

Experimental

Matched Description: … of bactericidal and tumoricidal effects [A31745]. ... The overall result of MDP recognition leads to the production of proinflammatory cytokines and promotion ... therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower 5-year …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Ixabepilone

Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...

Approved

Investigational

Matched Description: … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. ... Ixabepilone is a semisynthetic analogue of epothilone B. ... It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Dibenzepin

Dibenzepin is approved for use in Europe.

Approved

Matched Categories: … Non-Selective Monoamine Reuptake Inhibitors ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Azelastine

Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...

Approved

Matched Description: … allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis ... seasonal allergic rhinitis in patients 6 years of age and older. ... Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of …
Matched Mixtures name: … Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Categories: … Decongestants and Antiallergics ... Histamine H1 Antagonists, Non-Sedating …

Pegaptanib

Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.

Approved

Investigational

Matched Description: … neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Meticrane

Meticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure .

Approved

Matched Description: … It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure [L5647 …
Matched Categories: … combinations of sulfonamides ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.

Approved

Matched Categories: … Non Potassium Sparing Diuretics ... combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Trovafloxacin

Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective...

Approved

Investigational

Withdrawn

Matched Description: … by blocking the activity of DNA gyrase and topoisomerase IV. ... It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria …

Bendamustine

Bendamustine is a nitrogen mustard drug indicated for use in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen. Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl...

Approved

Investigational

Matched Description: … (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months ... It is active against both active and quiescent cells, although the exact mechanism of action is unknown ... of treatment with rituximab or a rituximab-containing regimen. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Nevirapine

A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.

Approved

Matched Description: … analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. ... A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Non-Nucleoside Reverse Transcriptase Inhibitors ... Inducers of Drug Clearance ... stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...

Approved

Matched Description: … [A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... tumour resistance patterns following treatment and toxic side effects that impact patient quality of …
Matched Categories: … Antineoplastic and Immunomodulating Agents …