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Displaying drugs 226 - 250 of 14784 in total

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...

Approved

Investigational

Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... However, it continues to be used in the treatment of Brugada syndrome, short QT syndrome and idiopathic …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Quinine and stereoisomer …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...

Approved

Nutraceutical

Vet approved

Matched Description: … Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... Up and Up Antacid and Pain Relief ... Sodium Citrate and Citric Acid …
Matched Categories: … Alimentary Tract and Metabolism …

Ixabepilone

Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...

Approved

Investigational

Matched Description: … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. ... Ixabepilone is a semisynthetic analogue of epothilone B. ... It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …

Azelastine

Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...

Approved

Matched Description: … allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis ... seasonal allergic rhinitis in patients 6 years of age and older. ... Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of …
Matched Mixtures name: … Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Categories: … Decongestants and Antiallergics ... Histamine H1 Antagonists, Non-Sedating …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.

Approved

Matched Categories: … Non Potassium Sparing Diuretics ... combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...

Approved

Matched Description: … surge, in females triggers ovulation and the development of the corpous luteum. ... Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... Its pharmacological action mimics the biological activity of endogenous LH; an acute rise of LH, or LH …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones …

Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...

Approved

Matched Description: … The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH ... and LH. ... O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones …

Nevirapine

A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.

Approved

Matched Description: … analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. ... A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside …
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Non-Nucleoside Reverse Transcriptase Inhibitors ... Inducers of Drug Clearance ... stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine …

Mifamurtide

Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...

Approved

Experimental

Matched Description: … of bactericidal and tumoricidal effects [A31745]. ... The overall result of MDP recognition leads to the production of proinflammatory cytokines and promotion ... therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower 5-year …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Pegaptanib

Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.

Approved

Investigational

Matched Description: … neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Rupatadine

Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...

Approved

Matched Description: … adult use and liquid formulation for pediatric use. ... Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is ... used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria …
Matched Categories: … Histamine H1 Antagonists, Non-Sedating …

Etacrynic acid

A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...

Approved

Investigational

Matched Description: … A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction ... Henle, but also in the proximal and distal tubules. …
Matched Categories: … Non Potassium Sparing Diuretics ... Increased Diuresis at Loop of Henle …