Displaying drugs 2501 - 2525 of 3341 in total
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Description: … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal ... reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and …
Matched Salts name: … Alosetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Alosetron Hydrochloride …
Matched Salts name: … Alosetron hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Alosetron Hydrochloride …
Butenafine
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Salts name: … Butenafine hydrochloride …
Matched Products: … Butenafine Hydrochloride 1% ... Butenafine Hydrochloride ... Butenafine Hydrochloride Jock Itch …
Matched Salts name: … Butenafine hydrochloride …
Matched Products: … Butenafine Hydrochloride 1% ... Butenafine Hydrochloride ... Butenafine Hydrochloride Jock Itch …
Epinastine
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and …
Matched Salts name: … Epinastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Acid Reducers …
Matched Products: … Epinastine Hydrochloride ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) ... RELESTAT (EPINASTINE HYDROCHLORIDE OPTHALMIC SOLUTION) 0.5mg/ml …
Matched Salts name: … Epinastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Acid Reducers …
Matched Products: … Epinastine Hydrochloride ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) ... RELESTAT (EPINASTINE HYDROCHLORIDE OPTHALMIC SOLUTION) 0.5mg/ml …
Phenoxybenzamine
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. ... An alpha-adrenergic antagonist with long duration of action. …
Matched Salts name: … Phenoxybenzamine hydrochloride …
Matched Categories: … Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Phenoxybenzamine Hydrochloride ... Phenoxybenzamine hydrochloride …
Matched Salts name: … Phenoxybenzamine hydrochloride …
Matched Categories: … Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Phenoxybenzamine Hydrochloride ... Phenoxybenzamine hydrochloride …
Algenpantucel-L
Investigational
Matched Synonyms: … Alpha (1,3) galactosyltransferase tumor vaccine ... Alpha-1,3-galactosyltransferase-expressing allogeneic pancreatic tumor cell vaccine …
Vasopressin
Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … eighth amino acids. ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … 2-(β-methylaminoethyl)pyridine ... 2-[2-(methylamino)ethyl]pyridine …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Isoxsuprine
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. ... It is used in the treatment of peripheral vascular disease and in premature labor. …
Matched Salts name: … Isoxsuprine hydrochloride …
Matched Products: … Isoxsuprine Hydrochloride ... ISOXSUPRINE HYDROCHLORIDE …
Matched Salts name: … Isoxsuprine hydrochloride …
Matched Products: … Isoxsuprine Hydrochloride ... ISOXSUPRINE HYDROCHLORIDE …
Daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Description: … , used in treatment of leukemia and other neoplasms. ... A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others …
Matched Salts name: … Daunorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Daunorubicin Hydrochloride ... Daunorubicin Hydrochloride Injection ... Daunorubicin Hydrochloride for Injection …
Matched Salts name: … Daunorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Daunorubicin Hydrochloride ... Daunorubicin Hydrochloride Injection ... Daunorubicin Hydrochloride for Injection …
Pyridoxal phosphate
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-monophosphoric acid ester …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine ... phosphate (pyridoxamine). ... (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Description: … During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine ... phosphate (pyridoxamine). ... (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. …
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Formebolone
Formebolone, a derivative of androstane, is an anabolic androgenic steroid. It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. It is also classified by the US Drug Enforcement Administration as Schedule III drug in the Controlled Substances Act. It...
Experimental
Illicit
Matched Synonyms: … 2-Formyl-17-alpha-methylandrosta-1,4-diene-11-alpha,17-beta-diol-3-one ... 2-Formyl-11-alpha-hydroxy-delta(sup 1)-methyltestosterone ... 11-alpha,17-beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde …
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened ... It has been used experimentally in the treatment of growth retardation, and has been noted to increase …
Matched Categories: … Testosterone and derivatives …
Matched Description: … It is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened ... It has been used experimentally in the treatment of growth retardation, and has been noted to increase …
Matched Categories: … Testosterone and derivatives …
THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE
Experimental
Matched Name: … THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE …
Matched Iupac: … N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide …
Matched Iupac: … N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxopyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Glucagon-like peptide II (2-glycine) (human) …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant ... Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant ... Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Various Alimentary Tract and Metabolism Products …
Ephedrine
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine …
Matched Salts name: … Ephedrine hydrochloride …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic alpha-Agonists ... Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Epinephrine and similars …
Matched Products: … EPHEDRINE HYDROCHLORIDE ... Ephedrine Hydrochloride ... Ephedrine Hydrochloride Tablets 25mg …
Matched Salts name: … Ephedrine hydrochloride …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic alpha-Agonists ... Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Epinephrine and similars …
Matched Products: … EPHEDRINE HYDROCHLORIDE ... Ephedrine Hydrochloride ... Ephedrine Hydrochloride Tablets 25mg …
(-)-menthol 1-propylene glycol carbonate
Experimental
Matched Synonyms: … Carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester …
L-Acetylleucine
Investigational
Matched Synonyms: … (s)-2-acetamido-4-methylpentanoic acid …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-acetamido-4-methylpentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain …
rAAV1-CB-hAAT
rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.
Investigational
Matched Synonyms: … recombinant adeno-associated virus alpha 1-antitrypsin vector …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Matched Description: … rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector. …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetate …
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Iupac: … 2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin-1-yl]-2-oxoethyl]amino}acetate …
Matched Description: … intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and ... would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and …
Matched Categories: … Blood and Blood Forming Organs …
Cathinone
Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat). Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that its structure is a ketone. Other amphetamines to share...
Illicit
Matched Synonyms: … alpha-Aminopropiophenone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Matched Description: … Closely related to ephedrine, cathine and other amphetamines, it is probably the main contributor to ... Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone …
Amiodarone
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved …
Matched Salts name: … Amiodarone hydrochloride …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Potassium Channel Blockers ... alpha-Galactosidase, antagonists & inhibitors …
Matched Products: … Amiodarone Hydrochloride ... Amiodarone hydrochloride ... AMIODARONE HYDROCHLORIDE …
Matched Salts name: … Amiodarone hydrochloride …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Potassium Channel Blockers ... alpha-Galactosidase, antagonists & inhibitors …
Matched Products: … Amiodarone Hydrochloride ... Amiodarone hydrochloride ... AMIODARONE HYDROCHLORIDE …
Cefoperazone
Cefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against Pseudomonas infections. It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. While its...
Approved
Investigational
Matched Synonyms: … amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Mixtures name: … CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM …
Matched Salts name: … Cefoperazone sodium …
Matched Products: … CEFOPERAZONE SODIUM …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections ... organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and …
Matched Mixtures name: … CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM ... CEFOPERAZONE SODIUM - SULBACTAM SODIUM …
Matched Salts name: … Cefoperazone sodium …
Matched Products: … CEFOPERAZONE SODIUM …
Posaconazole
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Description: … Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POSACONAZOLO BIOCON …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POSACONAZOLO BIOCON …
Asundexian
Asundexian is under investigation in clinical trial NCT05686070 (A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke).
Investigational
Matched Synonyms: … -ethyl-5-methoxy-2-oxo-, (.alpha.s)- ... 4-(aminocarbonyl)-3-fluorophenyl)-4-(5-chloro-2-(4-(trifluoromethyl)-1h-1,2,3-triazol-1-yl)phenyl)-.alpha …
Displaying drugs 2501 - 2525 of 3341 in total